Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging

Near-infrared fluorescent proteins are non-invasive probes for deep tissue imaging, but because of the dimeric state they perform poorly in protein labelling. Here, the authors engineered three spectrally resolvable monomeric near-infrared probes with improved brightness for multiscale imaging.

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Autores principales:	Daria M. Shcherbakova, Mikhail Baloban, Alexander V. Emelyanov, Michael Brenowitz, Peng Guo, Vladislav V. Verkhusha
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d65af6816dd54a51a577635c42aa4e40
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spelling	oai:doaj.org-article:d65af6816dd54a51a577635c42aa4e402021-12-02T14:39:11ZBright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging10.1038/ncomms124052041-1723https://doaj.org/article/d65af6816dd54a51a577635c42aa4e402016-08-01T00:00:00Zhttps://doi.org/10.1038/ncomms12405https://doaj.org/toc/2041-1723Near-infrared fluorescent proteins are non-invasive probes for deep tissue imaging, but because of the dimeric state they perform poorly in protein labelling. Here, the authors engineered three spectrally resolvable monomeric near-infrared probes with improved brightness for multiscale imaging.Daria M. ShcherbakovaMikhail BalobanAlexander V. EmelyanovMichael BrenowitzPeng GuoVladislav V. VerkhushaNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Daria M. Shcherbakova Mikhail Baloban Alexander V. Emelyanov Michael Brenowitz Peng Guo Vladislav V. Verkhusha Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
description	Near-infrared fluorescent proteins are non-invasive probes for deep tissue imaging, but because of the dimeric state they perform poorly in protein labelling. Here, the authors engineered three spectrally resolvable monomeric near-infrared probes with improved brightness for multiscale imaging.
format	article
author	Daria M. Shcherbakova Mikhail Baloban Alexander V. Emelyanov Michael Brenowitz Peng Guo Vladislav V. Verkhusha
author_facet	Daria M. Shcherbakova Mikhail Baloban Alexander V. Emelyanov Michael Brenowitz Peng Guo Vladislav V. Verkhusha
author_sort	Daria M. Shcherbakova
title	Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
title_short	Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
title_full	Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
title_fullStr	Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
title_full_unstemmed	Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
title_sort	bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/d65af6816dd54a51a577635c42aa4e40
work_keys_str_mv	AT dariamshcherbakova brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging AT mikhailbaloban brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging AT alexandervemelyanov brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging AT michaelbrenowitz brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging AT pengguo brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging AT vladislavvverkhusha brightmonomericnearinfraredfluorescentproteinsastagsandbiosensorsformultiscaleimaging
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Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging

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