Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

Antigen presenting cells induce CD4+ T helper (Th) differentiation upon pathogen encounters. Here the authors use fluorescently-labeled bacteria, helminth and fungi to track and describe the functions of IRF4+ migratory type 2 dendritic cells and monocytes in the specific induction of Th1, Th2 or Th...

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Autores principales:	Kerry L. Hilligan, Shiau-Choot Tang, Evelyn J. Hyde, Elsa Roussel, Johannes U. Mayer, Jianping Yang, Kirsty A. Wakelin, Alfonso J. Schmidt, Lisa M. Connor, Alan Sher, Andrew S. MacDonald, Franca Ronchese
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d65f3d80f398424cae180d6d1bb01a61
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spelling	oai:doaj.org-article:d65f3d80f398424cae180d6d1bb01a612021-12-02T15:39:25ZDermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles10.1038/s41467-020-19463-92041-1723https://doaj.org/article/d65f3d80f398424cae180d6d1bb01a612020-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-19463-9https://doaj.org/toc/2041-1723Antigen presenting cells induce CD4+ T helper (Th) differentiation upon pathogen encounters. Here the authors use fluorescently-labeled bacteria, helminth and fungi to track and describe the functions of IRF4+ migratory type 2 dendritic cells and monocytes in the specific induction of Th1, Th2 or Th17 responses following skin inoculation.Kerry L. HilliganShiau-Choot TangEvelyn J. HydeElsa RousselJohannes U. MayerJianping YangKirsty A. WakelinAlfonso J. SchmidtLisa M. ConnorAlan SherAndrew S. MacDonaldFranca RoncheseNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Kerry L. Hilligan Shiau-Choot Tang Evelyn J. Hyde Elsa Roussel Johannes U. Mayer Jianping Yang Kirsty A. Wakelin Alfonso J. Schmidt Lisa M. Connor Alan Sher Andrew S. MacDonald Franca Ronchese Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
description	Antigen presenting cells induce CD4+ T helper (Th) differentiation upon pathogen encounters. Here the authors use fluorescently-labeled bacteria, helminth and fungi to track and describe the functions of IRF4+ migratory type 2 dendritic cells and monocytes in the specific induction of Th1, Th2 or Th17 responses following skin inoculation.
format	article
author	Kerry L. Hilligan Shiau-Choot Tang Evelyn J. Hyde Elsa Roussel Johannes U. Mayer Jianping Yang Kirsty A. Wakelin Alfonso J. Schmidt Lisa M. Connor Alan Sher Andrew S. MacDonald Franca Ronchese
author_facet	Kerry L. Hilligan Shiau-Choot Tang Evelyn J. Hyde Elsa Roussel Johannes U. Mayer Jianping Yang Kirsty A. Wakelin Alfonso J. Schmidt Lisa M. Connor Alan Sher Andrew S. MacDonald Franca Ronchese
author_sort	Kerry L. Hilligan
title	Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
title_short	Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
title_full	Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
title_fullStr	Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
title_full_unstemmed	Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles
title_sort	dermal irf4+ dendritic cells and monocytes license cd4+ t helper cells to distinct cytokine profiles
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d65f3d80f398424cae180d6d1bb01a61
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Dermal IRF4+ dendritic cells and monocytes license CD4+ T helper cells to distinct cytokine profiles

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