High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo.

High-purity preparation of HSV-2 vaccine candidate ACAM529 is immunogenic and efficacious in vivo.

Genital herpes is a sexually transmitted infection (STI) caused by herpes simplex virus 2 (HSV-2) and to a lesser extent herpes simplex virus 1 (HSV-1). Infection by HSV-2 is life-long and is associated with significant cost to healthcare systems and social stigma despite the highly prevalent nature...

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Bibliographic Details
Main Authors: Sophia T Mundle, Hector Hernandez, John Hamberger, John Catalan, Changhong Zhou, Svetlana Stegalkina, Andrea Tiffany, Harry Kleanthous, Simon Delagrave, Stephen F Anderson
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2013
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/d67d7fbcea1545a78cf5d2f5c0f3bbb7
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