Green synthesis of gold nanoparticles using plant extracts as reducing agents

Paz Elia,1 Raya Zach,1 Sharon Hazan,2 Sofiya Kolusheva,2 Ze’ev Porat,1,3 Yehuda Zeiri1,3 1Department of Biomedical Engineering, 2Ilse Katz Institute of Nanotechnology, Ben-Gurion University of the Negev, 3Division of Chemistry, Negev Nuclear Research Center Beersheba, Israel Abstract: G...

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Autores principales:	Elia P, Zach R, Hazan S, Kolusheva S, Porat Z, Zeiri Y
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2014
Materias:	Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d68231bf19d34cdbb82f30b03a8a4a03
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spelling	oai:doaj.org-article:d68231bf19d34cdbb82f30b03a8a4a032021-12-02T05:10:44ZGreen synthesis of gold nanoparticles using plant extracts as reducing agents1178-2013https://doaj.org/article/d68231bf19d34cdbb82f30b03a8a4a032014-08-01T00:00:00Zhttp://www.dovepress.com/green-synthesis-of-gold-nanoparticles-using-plant-extracts-as-reducing-peer-reviewed-article-IJNhttps://doaj.org/toc/1178-2013 Paz Elia,1 Raya Zach,1 Sharon Hazan,2 Sofiya Kolusheva,2 Ze’ev Porat,1,3 Yehuda Zeiri1,3 1Department of Biomedical Engineering, 2Ilse Katz Institute of Nanotechnology, Ben-Gurion University of the Negev, 3Division of Chemistry, Negev Nuclear Research Center Beersheba, Israel Abstract: Gold nanoparticles (GNPs) were prepared using four different plant extracts as reducing and stabilizing agents. The extracts were obtained from the following plants: Salvia officinalis, Lippia citriodora, Pelargonium graveolens and Punica granatum. The size distributions of the GNPs were measured using three different methods: dynamic light scattering, nanoparticle-tracking analysis and analysis of scanning electron microscopy images. The three methods yielded similar size distributions. Biocompatibility was examined by correlation of L-cell growth in the presence of different amounts of GNPs. All GNPs showed good biocompatibility and good stability for over 3 weeks. Therefore, they can be used for imaging and drug-delivery applications in the human body. High-resolution transmission electron microscopy was used to view the shapes of the larger GNPs, while infrared spectroscopy was employed to characterize the various functional groups in the organic layer that stabilize the particles. Finally, active ingredients in the plant extract that might be involved in the formation of GNPs are proposed, based on experiments with pure antioxidants that are known to exist in that plant. Keywords: gold nanoparticles, Lippia citriodora, Salvia officinalis, Pelargonium graveolens, Punica granatum, antioxidants, size distribution, zeta potentialElia PZach RHazan SKolusheva SPorat ZZeiri YDove Medical PressarticleMedicine (General)R5-920ENInternational Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 4007-4021 (2014)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine (General) R5-920
spellingShingle	Medicine (General) R5-920 Elia P Zach R Hazan S Kolusheva S Porat Z Zeiri Y Green synthesis of gold nanoparticles using plant extracts as reducing agents
description	Paz Elia,1 Raya Zach,1 Sharon Hazan,2 Sofiya Kolusheva,2 Ze’ev Porat,1,3 Yehuda Zeiri1,3 1Department of Biomedical Engineering, 2Ilse Katz Institute of Nanotechnology, Ben-Gurion University of the Negev, 3Division of Chemistry, Negev Nuclear Research Center Beersheba, Israel Abstract: Gold nanoparticles (GNPs) were prepared using four different plant extracts as reducing and stabilizing agents. The extracts were obtained from the following plants: Salvia officinalis, Lippia citriodora, Pelargonium graveolens and Punica granatum. The size distributions of the GNPs were measured using three different methods: dynamic light scattering, nanoparticle-tracking analysis and analysis of scanning electron microscopy images. The three methods yielded similar size distributions. Biocompatibility was examined by correlation of L-cell growth in the presence of different amounts of GNPs. All GNPs showed good biocompatibility and good stability for over 3 weeks. Therefore, they can be used for imaging and drug-delivery applications in the human body. High-resolution transmission electron microscopy was used to view the shapes of the larger GNPs, while infrared spectroscopy was employed to characterize the various functional groups in the organic layer that stabilize the particles. Finally, active ingredients in the plant extract that might be involved in the formation of GNPs are proposed, based on experiments with pure antioxidants that are known to exist in that plant. Keywords: gold nanoparticles, Lippia citriodora, Salvia officinalis, Pelargonium graveolens, Punica granatum, antioxidants, size distribution, zeta potential
format	article
author	Elia P Zach R Hazan S Kolusheva S Porat Z Zeiri Y
author_facet	Elia P Zach R Hazan S Kolusheva S Porat Z Zeiri Y
author_sort	Elia P
title	Green synthesis of gold nanoparticles using plant extracts as reducing agents
title_short	Green synthesis of gold nanoparticles using plant extracts as reducing agents
title_full	Green synthesis of gold nanoparticles using plant extracts as reducing agents
title_fullStr	Green synthesis of gold nanoparticles using plant extracts as reducing agents
title_full_unstemmed	Green synthesis of gold nanoparticles using plant extracts as reducing agents
title_sort	green synthesis of gold nanoparticles using plant extracts as reducing agents
publisher	Dove Medical Press
publishDate	2014
url	https://doaj.org/article/d68231bf19d34cdbb82f30b03a8a4a03
work_keys_str_mv	AT eliap greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents AT zachr greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents AT hazans greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents AT kolushevas greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents AT poratz greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents AT zeiriy greensynthesisofgoldnanoparticlesusingplantextractsasreducingagents
_version_	1718400563159236608

Green synthesis of gold nanoparticles using plant extracts as reducing agents

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