Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum.

Targeting iron acquisition blocks infection with the fungal pathogens Aspergillus fumigatus and Fusarium oxysporum.

Filamentous fungi are an important cause of pulmonary and systemic morbidity and mortality, and also cause corneal blindness and visual impairment worldwide. Utilizing in vitro neutrophil killing assays and a model of fungal infection of the cornea, we demonstrated that Dectin-1 dependent IL-6 produ...

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Detalles Bibliográficos
Autores principales: Sixto M Leal, Sanhita Roy, Chairut Vareechon, Steven deJesus Carrion, Heather Clark, Manuel S Lopez-Berges, Antonio Di Pietro, Marcus Schrettl, Nicola Beckmann, Bernhard Redl, Hubertus Haas, Eric Pearlman
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Immunologic diseases. Allergy
RC581-607
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/d68745bffe404aedb98f88c87cd843dd
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