Electro-steric opening of the clc-2 chloride channel gate
Abstract The widely expressed two-pore homodimeric inward rectifier CLC-2 chloride channel regulates transepithelial chloride transport, extracellular chloride homeostasis, and neuronal excitability. Each pore is independently gated at hyperpolarized voltages by a conserved pore glutamate. Presumabl...
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Autores principales: | José J. De Jesús-Pérez, G. Arlette Méndez-Maldonado, Ana E. López-Romero, David Esparza-Jasso, Irma L. González-Hernández, Víctor De la Rosa, Roberto Gastélum-Garibaldi, Jorge E. Sánchez-Rodríguez, Jorge Arreola |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d68ca9a572f94156b3003b15ab5f24b7 |
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