Electro-steric opening of the clc-2 chloride channel gate

Electro-steric opening of the clc-2 chloride channel gate

Abstract The widely expressed two-pore homodimeric inward rectifier CLC-2 chloride channel regulates transepithelial chloride transport, extracellular chloride homeostasis, and neuronal excitability. Each pore is independently gated at hyperpolarized voltages by a conserved pore glutamate. Presumabl...

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Main Authors: José J. De Jesús-Pérez, G. Arlette Méndez-Maldonado, Ana E. López-Romero, David Esparza-Jasso, Irma L. González-Hernández, Víctor De la Rosa, Roberto Gastélum-Garibaldi, Jorge E. Sánchez-Rodríguez, Jorge Arreola
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/d68ca9a572f94156b3003b15ab5f24b7
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https://doaj.org/article/d68ca9a572f94156b3003b15ab5f24b7

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