Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial

Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial

Abstract Thalidomide induces γ-globin expression in erythroid progenitor cells, but its efficacy on patients with transfusion-dependent β-thalassemia (TDT) remains unclear. In this phase 2, multi-center, randomized, double-blind clinical trial, we aimed to determine the safety and efficacy of thalid...

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Autores principales: Jiang-Ming Chen, Wei-Jian Zhu, Jie Liu, Gui-Zhen Wang, Xiao-Qin Chen, Yun Tan, Wei-Wei Xu, Li-Wei Qu, Jin-Yan Li, Huan-Ju Yang, Lan Huang, Ning Cai, Wei-Da Wang, Ken Huang, Jian-Quan Xu, Guo-Hui Li, Sheng He, Tian-Ying Luo, Yi Huang, Song-Hua Liu, Wen-Qiang Wu, Qi-Yang Lu, Mei-Guang Zhou, Shu-Ying Chen, Rong-Lan Li, Mei-Ling Hu, Ying Huang, Jin-Hua Wei, Jun-Min Li, Sai-Juan Chen, Guang-Biao Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
Materias:
Medicine
R
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/d69983278793481ea84af70c5501262f
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https://doaj.org/article/d69983278793481ea84af70c5501262f

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