Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center

Hani Almoallim,1– 3 Rola Hassan,2,3 Mohamed Cheikh,2,3 Hanan Faruqui,2 Reem Alquraa,2 Ayman Eissa,2 Aous Alhazmi,3 Roaa Alsolaimani,2,4 Nahed Janoudi2 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Internal Medicine Department, Doctor Soliman Fa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Almoallim H, Hassan R, Cheikh M, Faruqui H, Alquraa R, Eissa A, Alhazmi A, Alsolaimani R, Janoudi N
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2020
Materias:	rheumatoid arthritis disease modifying antirheumatic drugs biologics tnf blockers registry remission rates. Diseases of the musculoskeletal system RC925-935
Acceso en línea:	https://doaj.org/article/d699f72f513d4e31aa12b8db2f19d2f4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d699f72f513d4e31aa12b8db2f19d2f4
record_format	dspace
spelling	oai:doaj.org-article:d699f72f513d4e31aa12b8db2f19d2f42021-12-02T09:26:55ZRheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center1179-156Xhttps://doaj.org/article/d699f72f513d4e31aa12b8db2f19d2f42020-08-01T00:00:00Zhttps://www.dovepress.com/rheumatoid-arthritis-saudi-database-rasd-disease-characteristics-and-r-peer-reviewed-article-OARRRhttps://doaj.org/toc/1179-156XHani Almoallim,1– 3 Rola Hassan,2,3 Mohamed Cheikh,2,3 Hanan Faruqui,2 Reem Alquraa,2 Ayman Eissa,2 Aous Alhazmi,3 Roaa Alsolaimani,2,4 Nahed Janoudi2 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Internal Medicine Department, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 3Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, Saudi Arabia; 4Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Rola Hassan; Hani Almoallim Email r.toufiq@hotmail.com; hanialmoallim@gmail.comBackground: National Registries are essential to direct current practice. Rheumatoid arthritis (RA) registries in the middle east and North Africa remain scarcely represented.Objective: To describe a population of Saudi RA patients and to compare the findings to internationally reported data.Methods: This is an observational study that was conducted at Doctor Soliman Fakeeh Hospital (DSFH) in Saudi Arabia. The study ran from 2014 to 2018 using a pool of 433 patients. Inclusion criteria included adults older than 18 years of age who fulfilled the 2010 American College of Rheumatology criteria for the diagnosis of RA and who were also regular visitors in our rheumatology clinics. Data were collected directly from patients and entered in a specially designed program.Results: At initial presentation, 45.5% had demonstrated active disease (moderate or high disease activity) based on DAS-28-CRP scores, while 54.5% were in low disease activity or remission. The remission rates after 1 year had increased to 79.6% (345 patients), while 9.7% (42 patients) and 10.6% (46 patients) had low disease activity and moderate disease activity, respectively. It was also found that the female gender, higher Health Assessment Questionnaire-Disability Index (HAQ-DI) and longer lag1/lag2 periods were associated with higher disease activity in our population.Conclusion: We detected higher remission rates at 1 year of follow-up. This could be attributed to many factors, including good referral systems with easier access to biologics. We aim to expand this registry to the national level.Keywords: rheumatoid arthritis, disease-modifying antirheumatic drugs, biologics, TNF blockers, registry, remission ratesAlmoallim HHassan RCheikh MFaruqui HAlquraa REissa AAlhazmi AAlsolaimani RJanoudi NDove Medical Pressarticlerheumatoid arthritisdisease modifying antirheumatic drugsbiologicstnf blockersregistryremission rates.Diseases of the musculoskeletal systemRC925-935ENOpen Access Rheumatology: Research and Reviews, Vol Volume 12, Pp 139-145 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	rheumatoid arthritis disease modifying antirheumatic drugs biologics tnf blockers registry remission rates. Diseases of the musculoskeletal system RC925-935
spellingShingle	rheumatoid arthritis disease modifying antirheumatic drugs biologics tnf blockers registry remission rates. Diseases of the musculoskeletal system RC925-935 Almoallim H Hassan R Cheikh M Faruqui H Alquraa R Eissa A Alhazmi A Alsolaimani R Janoudi N Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
description	Hani Almoallim,1– 3 Rola Hassan,2,3 Mohamed Cheikh,2,3 Hanan Faruqui,2 Reem Alquraa,2 Ayman Eissa,2 Aous Alhazmi,3 Roaa Alsolaimani,2,4 Nahed Janoudi2 1Department of Medicine, Faculty of Medicine, Umm Alqura University, Makkah, Saudi Arabia; 2Internal Medicine Department, Doctor Soliman Fakeeh Hospital, Jeddah, Saudi Arabia; 3Alzaidi Chair of Research in Rheumatic Diseases, Umm Alqura University, Makkah, Saudi Arabia; 4Department of Medicine, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Rola Hassan; Hani Almoallim Email r.toufiq@hotmail.com; hanialmoallim@gmail.comBackground: National Registries are essential to direct current practice. Rheumatoid arthritis (RA) registries in the middle east and North Africa remain scarcely represented.Objective: To describe a population of Saudi RA patients and to compare the findings to internationally reported data.Methods: This is an observational study that was conducted at Doctor Soliman Fakeeh Hospital (DSFH) in Saudi Arabia. The study ran from 2014 to 2018 using a pool of 433 patients. Inclusion criteria included adults older than 18 years of age who fulfilled the 2010 American College of Rheumatology criteria for the diagnosis of RA and who were also regular visitors in our rheumatology clinics. Data were collected directly from patients and entered in a specially designed program.Results: At initial presentation, 45.5% had demonstrated active disease (moderate or high disease activity) based on DAS-28-CRP scores, while 54.5% were in low disease activity or remission. The remission rates after 1 year had increased to 79.6% (345 patients), while 9.7% (42 patients) and 10.6% (46 patients) had low disease activity and moderate disease activity, respectively. It was also found that the female gender, higher Health Assessment Questionnaire-Disability Index (HAQ-DI) and longer lag1/lag2 periods were associated with higher disease activity in our population.Conclusion: We detected higher remission rates at 1 year of follow-up. This could be attributed to many factors, including good referral systems with easier access to biologics. We aim to expand this registry to the national level.Keywords: rheumatoid arthritis, disease-modifying antirheumatic drugs, biologics, TNF blockers, registry, remission rates
format	article
author	Almoallim H Hassan R Cheikh M Faruqui H Alquraa R Eissa A Alhazmi A Alsolaimani R Janoudi N
author_facet	Almoallim H Hassan R Cheikh M Faruqui H Alquraa R Eissa A Alhazmi A Alsolaimani R Janoudi N
author_sort	Almoallim H
title	Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
title_short	Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
title_full	Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
title_fullStr	Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
title_full_unstemmed	Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center
title_sort	rheumatoid arthritis saudi database (rasd): disease characteristics and remission rates in a tertiary care center
publisher	Dove Medical Press
publishDate	2020
url	https://doaj.org/article/d699f72f513d4e31aa12b8db2f19d2f4
work_keys_str_mv	AT almoallimh rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT hassanr rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT cheikhm rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT faruquih rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT alquraar rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT eissaa rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT alhazmia rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT alsolaimanir rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter AT janoudin rheumatoidarthritissaudidatabaserasddiseasecharacteristicsandremissionratesinatertiarycarecenter
_version_	1718398152760885248

Rheumatoid Arthritis Saudi Database (RASD): Disease Characteristics and Remission Rates in a Tertiary Care Center

Ejemplares similares