Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability
Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, the authors perform genome- and epigenome-wide analyses from normal and ACC pancreatic tissue that identify aberrations in genome stability and cell cycle control.
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Nature Portfolio
2017
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oai:doaj.org-article:d69c18b22f7a4f1a816b05e01db8f13e2021-12-02T17:06:05ZGenome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability10.1038/s41467-017-01118-x2041-1723https://doaj.org/article/d69c18b22f7a4f1a816b05e01db8f13e2017-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01118-xhttps://doaj.org/toc/2041-1723Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, the authors perform genome- and epigenome-wide analyses from normal and ACC pancreatic tissue that identify aberrations in genome stability and cell cycle control.Cornelia JäkelFrank BergmannReka TothYassen AssenovDaniel van der DuinOliver StrobelThomas HankGünter KlöppelCraig DorrellMarkus GrompeJoshua MossYuval DorPeter SchirmacherChristoph PlassOdilia PopandaPeter SchmezerNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-10 (2017) |
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DOAJ |
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DOAJ |
| language |
EN |
| topic |
Science Q |
| spellingShingle |
Science Q Cornelia Jäkel Frank Bergmann Reka Toth Yassen Assenov Daniel van der Duin Oliver Strobel Thomas Hank Günter Klöppel Craig Dorrell Markus Grompe Joshua Moss Yuval Dor Peter Schirmacher Christoph Plass Odilia Popanda Peter Schmezer Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| description |
Pancreatic acinar cell carcinoma (ACC) is an aggressive exocrine tumor with largely unknown biology. Here, the authors perform genome- and epigenome-wide analyses from normal and ACC pancreatic tissue that identify aberrations in genome stability and cell cycle control. |
| format |
article |
| author |
Cornelia Jäkel Frank Bergmann Reka Toth Yassen Assenov Daniel van der Duin Oliver Strobel Thomas Hank Günter Klöppel Craig Dorrell Markus Grompe Joshua Moss Yuval Dor Peter Schirmacher Christoph Plass Odilia Popanda Peter Schmezer |
| author_facet |
Cornelia Jäkel Frank Bergmann Reka Toth Yassen Assenov Daniel van der Duin Oliver Strobel Thomas Hank Günter Klöppel Craig Dorrell Markus Grompe Joshua Moss Yuval Dor Peter Schirmacher Christoph Plass Odilia Popanda Peter Schmezer |
| author_sort |
Cornelia Jäkel |
| title |
Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| title_short |
Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| title_full |
Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| title_fullStr |
Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| title_full_unstemmed |
Genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| title_sort |
genome-wide genetic and epigenetic analyses of pancreatic acinar cell carcinomas reveal aberrations in genome stability |
| publisher |
Nature Portfolio |
| publishDate |
2017 |
| url |
https://doaj.org/article/d69c18b22f7a4f1a816b05e01db8f13e |
| work_keys_str_mv |
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1718381759556485120 |