Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

Trapped ion mobility spectrometry and PASEF enable in-depth lipidomics from minimal sample amounts

Trapped ion mobility (TIMS)-mass spectrometry with parallel accumulation-serial fragmentation (PASEF) facilitates high-sensitivity proteomics experiments. Here, the authors expand TIMS and PASEF to small molecules and demonstrate fast and comprehensive lipidomics of low biological sample amounts.

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Detalles Bibliográficos
Autores principales: Catherine G. Vasilopoulou, Karolina Sulek, Andreas-David Brunner, Ningombam Sanjib Meitei, Ulrike Schweiger-Hufnagel, Sven W. Meyer, Aiko Barsch, Matthias Mann, Florian Meier
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Science
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Acceso en línea:https://doaj.org/article/d6a409c3b2024cd59469965a92c59566
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