Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides

O-glycosides and nucleosides are important biomolecules. Here, the authors developed a protocol for the synthesis of such molecules with a broad substrate scope using glycosyl ortho-(1-phenylvinyl)benzoates as glycosyl donors that allow for mild reaction conditions and high yields.

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Autores principales: Penghua Li, Haiqing He, Yunqin Zhang, Rui Yang, Lili Xu, Zixi Chen, Yingying Huang, Limei Bao, Guozhi Xiao
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d6a57ff3ce80403898dd019b1b9ffe6b
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spelling oai:doaj.org-article:d6a57ff3ce80403898dd019b1b9ffe6b2021-12-02T14:42:56ZGlycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides10.1038/s41467-020-14295-z2041-1723https://doaj.org/article/d6a57ff3ce80403898dd019b1b9ffe6b2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-14295-zhttps://doaj.org/toc/2041-1723O-glycosides and nucleosides are important biomolecules. Here, the authors developed a protocol for the synthesis of such molecules with a broad substrate scope using glycosyl ortho-(1-phenylvinyl)benzoates as glycosyl donors that allow for mild reaction conditions and high yields.Penghua LiHaiqing HeYunqin ZhangRui YangLili XuZixi ChenYingying HuangLimei BaoGuozhi XiaoNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Penghua Li
Haiqing He
Yunqin Zhang
Rui Yang
Lili Xu
Zixi Chen
Yingying Huang
Limei Bao
Guozhi Xiao
Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
description O-glycosides and nucleosides are important biomolecules. Here, the authors developed a protocol for the synthesis of such molecules with a broad substrate scope using glycosyl ortho-(1-phenylvinyl)benzoates as glycosyl donors that allow for mild reaction conditions and high yields.
format article
author Penghua Li
Haiqing He
Yunqin Zhang
Rui Yang
Lili Xu
Zixi Chen
Yingying Huang
Limei Bao
Guozhi Xiao
author_facet Penghua Li
Haiqing He
Yunqin Zhang
Rui Yang
Lili Xu
Zixi Chen
Yingying Huang
Limei Bao
Guozhi Xiao
author_sort Penghua Li
title Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
title_short Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
title_full Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
title_fullStr Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
title_full_unstemmed Glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both O-glycosides and nucleosides
title_sort glycosyl ortho-(1-phenylvinyl)benzoates versatile glycosyl donors for highly efficient synthesis of both o-glycosides and nucleosides
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/d6a57ff3ce80403898dd019b1b9ffe6b
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