Non-choroidal yellow melanoma showing positive staining with Sudan Black consistent with the presence of lipofuscin: a case report

A case of a predominantly yellow primary superficial spreading melanoma arising on the back of a 44-year-old woman is presented. Possible causes of the clinical and dermatoscopic yellow color are discussed. Staining with the histochemical stain, Sudan Black, revealed a differential uptake compared...

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Autores principales: Marie Hélène Jegou Penouil, Jean-Yves Gourhant, Catherine Segretin, David Weedon, Cliff Rosendahl
Formato: article
Lenguaje:EN
Publicado: Mattioli1885 2014
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Acceso en línea:https://doaj.org/article/d6abac6ca4ec47559b4b44e3899be876
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Sumario:A case of a predominantly yellow primary superficial spreading melanoma arising on the back of a 44-year-old woman is presented. Possible causes of the clinical and dermatoscopic yellow color are discussed. Staining with the histochemical stain, Sudan Black, revealed a differential uptake compared to a closely matched control melanoma. We speculate that the clinical and dermatoscopic yellow color could be due to the presence of increased amounts of the pigment lipofuscin, which is known to produce subtle orange color in some choroidal melanomas.