Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue

Abstract Gut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, man...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Mon-Chien Lee, Yi-Ju Hsu, Hsieh‐Hsun Ho, Yi‐Wei Kuo, Wen-Yang Lin, Shin-Yu Tsai, Wei-Ling Chen, Che-Li Lin, Chi-Chang Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d6ac49e7e357417d89cb4194067480ee
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d6ac49e7e357417d89cb4194067480ee
record_format	dspace
spelling	oai:doaj.org-article:d6ac49e7e357417d89cb4194067480ee2021-12-02T19:16:54ZEffectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue10.1038/s41598-021-98958-x2045-2322https://doaj.org/article/d6ac49e7e357417d89cb4194067480ee2021-09-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-98958-xhttps://doaj.org/toc/2045-2322Abstract Gut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, many studies have shown that probiotic supplementation can effectively improve sports performance. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of 2008 Olympic women's 48 kg weightlifting gold medalist and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0, 2.05 × 109, 4.10 × 109 and 1.03 × 1010 CFU/kg/day groups and were fed by oral gavage once daily for 4 weeks. The results showed that 4 weeks of PL-02 supplementation could significantly increase muscle mass, muscle strength and endurance performance, and hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise (p < 0.05). We believe that PL-02 can be used as a supplement to improve exercise performance and for its anti-fatigue effect.Mon-Chien LeeYi-Ju HsuHsieh‐Hsun HoYi‐Wei KuoWen-Yang LinShin-Yu TsaiWei-Ling ChenChe-Li LinChi-Chang HuangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Mon-Chien Lee Yi-Ju Hsu Hsieh‐Hsun Ho Yi‐Wei Kuo Wen-Yang Lin Shin-Yu Tsai Wei-Ling Chen Che-Li Lin Chi-Chang Huang Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
description	Abstract Gut microbiota is very important for energy metabolism and regulation, which in turn affect the health and physiological functions of the host, and provide energy required for exercise. Supplementation with probiotics may be one of the ways to change the gut microbiota. In recent years, many studies have shown that probiotic supplementation can effectively improve sports performance. In this study, we screened Lactobacillus plantarum (PL-02), a probiotic of human-origin, from the intestines of 2008 Olympic women's 48 kg weightlifting gold medalist and explored the role of PL-02 in improved exercise endurance performance, reduced fatigue biochemical parameters, and changes in body composition. Male Institute of Cancer Research (ICR) mice were assigned to 0, 2.05 × 109, 4.10 × 109 and 1.03 × 1010 CFU/kg/day groups and were fed by oral gavage once daily for 4 weeks. The results showed that 4 weeks of PL-02 supplementation could significantly increase muscle mass, muscle strength and endurance performance, and hepatic and muscular glycogen storage. Furthermore, PL-02 could significantly decrease lactate, blood urea nitrogen (BUN), ammonia, and creatine kinase (CK) levels after exercise (p < 0.05). We believe that PL-02 can be used as a supplement to improve exercise performance and for its anti-fatigue effect.
format	article
author	Mon-Chien Lee Yi-Ju Hsu Hsieh‐Hsun Ho Yi‐Wei Kuo Wen-Yang Lin Shin-Yu Tsai Wei-Ling Chen Che-Li Lin Chi-Chang Huang
author_facet	Mon-Chien Lee Yi-Ju Hsu Hsieh‐Hsun Ho Yi‐Wei Kuo Wen-Yang Lin Shin-Yu Tsai Wei-Ling Chen Che-Li Lin Chi-Chang Huang
author_sort	Mon-Chien Lee
title	Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
title_short	Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
title_full	Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
title_fullStr	Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
title_full_unstemmed	Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue
title_sort	effectiveness of human-origin lactobacillus plantarum pl-02 in improving muscle mass, exercise performance and anti-fatigue
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d6ac49e7e357417d89cb4194067480ee
work_keys_str_mv	AT monchienlee effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT yijuhsu effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT hsiehhsunho effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT yiweikuo effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT wenyanglin effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT shinyutsai effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT weilingchen effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT chelilin effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue AT chichanghuang effectivenessofhumanoriginlactobacillusplantarumpl02inimprovingmusclemassexerciseperformanceandantifatigue
_version_	1718376940639879168

Effectiveness of human-origin Lactobacillus plantarum PL-02 in improving muscle mass, exercise performance and anti-fatigue

Ejemplares similares