ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress

The ER increases in size upon stress in response to the UPR and is remodelled after the stressor is removed by a process called recov-ER-phagy. Here, the authors show remodelling to pre-stress ER size occurs by micro-ER-phagy requiring ESCRT-III components CHMP4B and VPS4A.

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Autores principales: Marisa Loi, Andrea Raimondi, Diego Morone, Maurizio Molinari
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d6b40ad97a5d4efa9a4258dae758c269
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spelling oai:doaj.org-article:d6b40ad97a5d4efa9a4258dae758c2692021-12-02T17:01:32ZESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress10.1038/s41467-019-12991-z2041-1723https://doaj.org/article/d6b40ad97a5d4efa9a4258dae758c2692019-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12991-zhttps://doaj.org/toc/2041-1723The ER increases in size upon stress in response to the UPR and is remodelled after the stressor is removed by a process called recov-ER-phagy. Here, the authors show remodelling to pre-stress ER size occurs by micro-ER-phagy requiring ESCRT-III components CHMP4B and VPS4A.Marisa LoiAndrea RaimondiDiego MoroneMaurizio MolinariNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Marisa Loi
Andrea Raimondi
Diego Morone
Maurizio Molinari
ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
description The ER increases in size upon stress in response to the UPR and is remodelled after the stressor is removed by a process called recov-ER-phagy. Here, the authors show remodelling to pre-stress ER size occurs by micro-ER-phagy requiring ESCRT-III components CHMP4B and VPS4A.
format article
author Marisa Loi
Andrea Raimondi
Diego Morone
Maurizio Molinari
author_facet Marisa Loi
Andrea Raimondi
Diego Morone
Maurizio Molinari
author_sort Marisa Loi
title ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
title_short ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
title_full ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
title_fullStr ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
title_full_unstemmed ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
title_sort escrt-iii-driven piecemeal micro-er-phagy remodels the er during recovery from er stress
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d6b40ad97a5d4efa9a4258dae758c269
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AT andrearaimondi escrtiiidrivenpiecemealmicroerphagyremodelstheerduringrecoveryfromerstress
AT diegomorone escrtiiidrivenpiecemealmicroerphagyremodelstheerduringrecoveryfromerstress
AT mauriziomolinari escrtiiidrivenpiecemealmicroerphagyremodelstheerduringrecoveryfromerstress
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