The role of memory in non-genetic inheritance and its impact on cancer treatment resistance.
Intra-tumour heterogeneity is a leading cause of treatment failure and disease progression in cancer. While genetic mutations have long been accepted as a primary mechanism of generating this heterogeneity, the role of phenotypic plasticity is becoming increasingly apparent as a driver of intra-tumo...
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Auteurs principaux: | Tyler Cassidy, Daniel Nichol, Mark Robertson-Tessi, Morgan Craig, Alexander R A Anderson |
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Format: | article |
Langue: | EN |
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Public Library of Science (PLoS)
2021
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Accès en ligne: | https://doaj.org/article/d6c120fed11b4ebeb8bb0479a0ce7d3f |
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