Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia

Pedro Caldana Gordon,1,2 Josefa Cynara Xavier,2 Mario Rodrigues Louz&atilde;21Department of Psychiatry, Faculdade de Medicina, Universidade de S&atilde;o Paulo, Brazil; 2Schizophrenia Research Program, Institute of Psychiatry, Hospital das Cl&iacute;nicas, Faculdade de Medici...

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Autores principales:	Gordon PC, Xavier JC, Louz&atilde; MR
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d6c4ed9cb3e4414dbbcc5c52d80fb2e9
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spelling	oai:doaj.org-article:d6c4ed9cb3e4414dbbcc5c52d80fb2e92021-12-02T00:54:29ZWeight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia1176-63281178-2021https://doaj.org/article/d6c4ed9cb3e4414dbbcc5c52d80fb2e92013-01-01T00:00:00Zhttp://www.dovepress.com/weight-gain-metabolic-disturbances-and-physical-health-care-in-a-brazi-a11980https://doaj.org/toc/1176-6328https://doaj.org/toc/1178-2021Pedro Caldana Gordon,1,2 Josefa Cynara Xavier,2 Mario Rodrigues Louz&atilde;21Department of Psychiatry, Faculdade de Medicina, Universidade de S&atilde;o Paulo, Brazil; 2Schizophrenia Research Program, Institute of Psychiatry, Hospital das Cl&iacute;nicas, Faculdade de Medicina, Universidade de S&atilde;o Paulo, BrazilBackground: In the last few decades, a large number of studies have produced compelling evidence that patients with schizophrenia are at increased risk for developing several medical conditions and diseases, including obesity, metabolic disturbances, and cardiovascular diseases. Several protocols have been designed with the aim of reducing such risk.Objective: To investigate current physical health status in a population of outpatients with schizophrenia.Methods: A cross-sectional study was conducted in our outpatient clinic, selecting subjects who met DSM-IV diagnosis criteria for schizophrenia. Data were collected regarding clinical characteristics, lifestyle, medication in use, and biometric and laboratory parameters.Results: A total of 261 patients were included. We found a high prevalence of elevated body mass index (BMI &gt; 25) (70%), dyslipidemia (73.2%), and metabolic syndrome (28.7%). Patients&#39; ages were associated with worsened lipid profiles, but other variables, such as disorder duration or type of antipsychotic in use, were not associated with any metabolic disturbance. Despite the increased prevalence of these conditions, only a small portion of the sample was under regular medical treatment.Conclusion: Outpatients with schizophrenia show signs of poor physical health conditions. These findings reinforce the need for an intensive and appropriate approach to assure that these patients receive adequate clinical referral and treatment.Keywords: psychosis, obesity, public health, antipsychotic drugs, cardiovascular disordersGordon PCXavier JCLouz&atilde; MRDove Medical PressarticleNeurosciences. Biological psychiatry. NeuropsychiatryRC321-571Neurology. Diseases of the nervous systemRC346-429ENNeuropsychiatric Disease and Treatment, Vol 2013, Iss default, Pp 133-138 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429
spellingShingle	Neurosciences. Biological psychiatry. Neuropsychiatry RC321-571 Neurology. Diseases of the nervous system RC346-429 Gordon PC Xavier JC Louz&atilde; MR Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
description	Pedro Caldana Gordon,1,2 Josefa Cynara Xavier,2 Mario Rodrigues Louz&atilde;21Department of Psychiatry, Faculdade de Medicina, Universidade de S&atilde;o Paulo, Brazil; 2Schizophrenia Research Program, Institute of Psychiatry, Hospital das Cl&iacute;nicas, Faculdade de Medicina, Universidade de S&atilde;o Paulo, BrazilBackground: In the last few decades, a large number of studies have produced compelling evidence that patients with schizophrenia are at increased risk for developing several medical conditions and diseases, including obesity, metabolic disturbances, and cardiovascular diseases. Several protocols have been designed with the aim of reducing such risk.Objective: To investigate current physical health status in a population of outpatients with schizophrenia.Methods: A cross-sectional study was conducted in our outpatient clinic, selecting subjects who met DSM-IV diagnosis criteria for schizophrenia. Data were collected regarding clinical characteristics, lifestyle, medication in use, and biometric and laboratory parameters.Results: A total of 261 patients were included. We found a high prevalence of elevated body mass index (BMI &gt; 25) (70%), dyslipidemia (73.2%), and metabolic syndrome (28.7%). Patients&#39; ages were associated with worsened lipid profiles, but other variables, such as disorder duration or type of antipsychotic in use, were not associated with any metabolic disturbance. Despite the increased prevalence of these conditions, only a small portion of the sample was under regular medical treatment.Conclusion: Outpatients with schizophrenia show signs of poor physical health conditions. These findings reinforce the need for an intensive and appropriate approach to assure that these patients receive adequate clinical referral and treatment.Keywords: psychosis, obesity, public health, antipsychotic drugs, cardiovascular disorders
format	article
author	Gordon PC Xavier JC Louz&atilde; MR
author_facet	Gordon PC Xavier JC Louz&atilde; MR
author_sort	Gordon PC
title	Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
title_short	Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
title_full	Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
title_fullStr	Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
title_full_unstemmed	Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia
title_sort	weight gain, metabolic disturbances, and physical health care in a brazilian sample of outpatients with schizophrenia
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/d6c4ed9cb3e4414dbbcc5c52d80fb2e9
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_version_	1718403466483728384

Weight gain, metabolic disturbances, and physical health care in a Brazilian sample of outpatients with schizophrenia

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