Identification of the periplasmic DNA receptor for natural transformation of Helicobacter pylori

Some bacteria can take up DNA molecules from the environment. Here, Damke et al. identify a DNA-binding protein in Helicobacter pylori that is required for DNA import into the periplasm and that interacts with an inner-membrane channel that translocates the DNA into the cytoplasm.

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Auteurs principaux: Prashant P. Damke, Anne Marie Di Guilmi, Paloma Fernández Varela, Christophe Velours, Stéphanie Marsin, Xavier Veaute, Mérick Machouri, Gaurav V. Gunjal, Desirazu N. Rao, Jean-Baptiste Charbonnier, J. Pablo Radicella
Format: article
Langue:EN
Publié: Nature Portfolio 2019
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Accès en ligne:https://doaj.org/article/d6cc5dff533e482ebd0d89385013b9ec
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Résumé:Some bacteria can take up DNA molecules from the environment. Here, Damke et al. identify a DNA-binding protein in Helicobacter pylori that is required for DNA import into the periplasm and that interacts with an inner-membrane channel that translocates the DNA into the cytoplasm.