Nonvirally modified autologous primary hepatocytes correct diabetes and prevent target organ injury in a large preclinical model.

<h4>Background</h4>Current gene- and cell-based therapies have significant limitations which impede widespread clinical application. Taking diabetes mellitus as a paradigm, we have sought to overcome these limitations by ex vivo electrotransfer of a nonviral insulin expression vector int...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Nelson K F Chen, Jen San Wong, Irene H C Kee, Siang Hui Lai, Choon Hua Thng, Wai Har Ng, Robert T H Ng, Soo Yong Tan, Shu Yen Lee, Mark E H Tan, Jaichandran Sivalingam, Pierce K H Chow, Oi Lian Kon
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2008
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d6d641e5934441eda05c41c85f05a2af
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Sea el primero en dejar un comentario!

Nonvirally modified autologous primary hepatocytes correct diabetes and prevent target organ injury in a large preclinical model.

Ejemplares similares