Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

The authors identify circular RNAs (circRNA) from human papillomavirus and show that circRNA-encoded E7 contributes to cancer cell growth in vitro and in tumor xenografts. Furthermore, circE7 is present in TCGA RNA-Seq data from HPV-positive cancers.

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Autores principales:	Jiawei Zhao, Eunice E. Lee, Jiwoong Kim, Rong Yang, Bahir Chamseddin, Chunyang Ni, Elona Gusho, Yang Xie, Cheng-Ming Chiang, Michael Buszczak, Xiaowei Zhan, Laimonis Laimins, Richard C. Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d6e2d14d8afd4ed6b39081f56f70355c
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spelling	oai:doaj.org-article:d6e2d14d8afd4ed6b39081f56f70355c2021-12-02T14:38:41ZTransforming activity of an oncoprotein-encoding circular RNA from human papillomavirus10.1038/s41467-019-10246-52041-1723https://doaj.org/article/d6e2d14d8afd4ed6b39081f56f70355c2019-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-10246-5https://doaj.org/toc/2041-1723The authors identify circular RNAs (circRNA) from human papillomavirus and show that circRNA-encoded E7 contributes to cancer cell growth in vitro and in tumor xenografts. Furthermore, circE7 is present in TCGA RNA-Seq data from HPV-positive cancers.Jiawei ZhaoEunice E. LeeJiwoong KimRong YangBahir ChamseddinChunyang NiElona GushoYang XieCheng-Ming ChiangMichael BuszczakXiaowei ZhanLaimonis LaiminsRichard C. WangNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jiawei Zhao Eunice E. Lee Jiwoong Kim Rong Yang Bahir Chamseddin Chunyang Ni Elona Gusho Yang Xie Cheng-Ming Chiang Michael Buszczak Xiaowei Zhan Laimonis Laimins Richard C. Wang Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
description	The authors identify circular RNAs (circRNA) from human papillomavirus and show that circRNA-encoded E7 contributes to cancer cell growth in vitro and in tumor xenografts. Furthermore, circE7 is present in TCGA RNA-Seq data from HPV-positive cancers.
format	article
author	Jiawei Zhao Eunice E. Lee Jiwoong Kim Rong Yang Bahir Chamseddin Chunyang Ni Elona Gusho Yang Xie Cheng-Ming Chiang Michael Buszczak Xiaowei Zhan Laimonis Laimins Richard C. Wang
author_facet	Jiawei Zhao Eunice E. Lee Jiwoong Kim Rong Yang Bahir Chamseddin Chunyang Ni Elona Gusho Yang Xie Cheng-Ming Chiang Michael Buszczak Xiaowei Zhan Laimonis Laimins Richard C. Wang
author_sort	Jiawei Zhao
title	Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
title_short	Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
title_full	Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
title_fullStr	Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
title_full_unstemmed	Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus
title_sort	transforming activity of an oncoprotein-encoding circular rna from human papillomavirus
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/d6e2d14d8afd4ed6b39081f56f70355c
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Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus

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