COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

Amila Suraweera et al. use a range of biochemical and in vitro cellular assays to examine the role of the COMMD4 in DNA repair. Their results suggest that COMMD4 interacts with the histone H2A-H2B during repair of double-stranded DNA breaks, thereby maintaining genomic stability by regulating chroma...

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Autores principales:	Amila Suraweera, Neha S. Gandhi, Sam Beard, Joshua T. Burgess, Laura V. Croft, Emma Bolderson, Ali Naqi, Nicholas W. Ashton, Mark N. Adams, Kienan I. Savage, Shu-Dong Zhang, Kenneth J. O’Byrne, Derek J. Richard
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/d6ec5b410c7346699b96af09c2c4016b
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spelling	oai:doaj.org-article:d6ec5b410c7346699b96af09c2c4016b2021-12-02T18:28:59ZCOMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks10.1038/s42003-021-01998-22399-3642https://doaj.org/article/d6ec5b410c7346699b96af09c2c4016b2021-04-01T00:00:00Zhttps://doi.org/10.1038/s42003-021-01998-2https://doaj.org/toc/2399-3642Amila Suraweera et al. use a range of biochemical and in vitro cellular assays to examine the role of the COMMD4 in DNA repair. Their results suggest that COMMD4 interacts with the histone H2A-H2B during repair of double-stranded DNA breaks, thereby maintaining genomic stability by regulating chromatin structure.Amila SuraweeraNeha S. GandhiSam BeardJoshua T. BurgessLaura V. CroftEmma BoldersonAli NaqiNicholas W. AshtonMark N. AdamsKienan I. SavageShu-Dong ZhangKenneth J. O’ByrneDerek J. RichardNature PortfolioarticleBiology (General)QH301-705.5ENCommunications Biology, Vol 4, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Amila Suraweera Neha S. Gandhi Sam Beard Joshua T. Burgess Laura V. Croft Emma Bolderson Ali Naqi Nicholas W. Ashton Mark N. Adams Kienan I. Savage Shu-Dong Zhang Kenneth J. O’Byrne Derek J. Richard COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
description	Amila Suraweera et al. use a range of biochemical and in vitro cellular assays to examine the role of the COMMD4 in DNA repair. Their results suggest that COMMD4 interacts with the histone H2A-H2B during repair of double-stranded DNA breaks, thereby maintaining genomic stability by regulating chromatin structure.
format	article
author	Amila Suraweera Neha S. Gandhi Sam Beard Joshua T. Burgess Laura V. Croft Emma Bolderson Ali Naqi Nicholas W. Ashton Mark N. Adams Kienan I. Savage Shu-Dong Zhang Kenneth J. O’Byrne Derek J. Richard
author_facet	Amila Suraweera Neha S. Gandhi Sam Beard Joshua T. Burgess Laura V. Croft Emma Bolderson Ali Naqi Nicholas W. Ashton Mark N. Adams Kienan I. Savage Shu-Dong Zhang Kenneth J. O’Byrne Derek J. Richard
author_sort	Amila Suraweera
title	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
title_short	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
title_full	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
title_fullStr	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
title_full_unstemmed	COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks
title_sort	commd4 functions with the histone h2a-h2b dimer for the timely repair of dna double-strand breaks
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d6ec5b410c7346699b96af09c2c4016b
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COMMD4 functions with the histone H2A-H2B dimer for the timely repair of DNA double-strand breaks

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