The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins

Atherosclerosis results from the accumulation of lipoproteins in the vascular wall. Here, Thierer et al. report the design of a chemiluminescent reporter for atherogenic lipoproteins using fusion of apolipoprotein-B to a luciferase enzyme, and find it bears potential for the identification of regula...

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Autores principales: James H. Thierer, Stephen C. Ekker, Steven A. Farber
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d6fe8db78b3a4164a8ddbb6eb1152a2f
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spelling oai:doaj.org-article:d6fe8db78b3a4164a8ddbb6eb1152a2f2021-12-02T16:51:00ZThe LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins10.1038/s41467-019-11259-w2041-1723https://doaj.org/article/d6fe8db78b3a4164a8ddbb6eb1152a2f2019-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-11259-whttps://doaj.org/toc/2041-1723Atherosclerosis results from the accumulation of lipoproteins in the vascular wall. Here, Thierer et al. report the design of a chemiluminescent reporter for atherogenic lipoproteins using fusion of apolipoprotein-B to a luciferase enzyme, and find it bears potential for the identification of regulators of lipoprotein metabolism in vivo.James H. ThiererStephen C. EkkerSteven A. FarberNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
James H. Thierer
Stephen C. Ekker
Steven A. Farber
The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
description Atherosclerosis results from the accumulation of lipoproteins in the vascular wall. Here, Thierer et al. report the design of a chemiluminescent reporter for atherogenic lipoproteins using fusion of apolipoprotein-B to a luciferase enzyme, and find it bears potential for the identification of regulators of lipoprotein metabolism in vivo.
format article
author James H. Thierer
Stephen C. Ekker
Steven A. Farber
author_facet James H. Thierer
Stephen C. Ekker
Steven A. Farber
author_sort James H. Thierer
title The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
title_short The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
title_full The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
title_fullStr The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
title_full_unstemmed The LipoGlo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
title_sort lipoglo reporter system for sensitive and specific monitoring of atherogenic lipoproteins
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d6fe8db78b3a4164a8ddbb6eb1152a2f
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