Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

Ureaplasma parvum is often isolated from intrauterine infections, which are associated with 40% of preterm births. Here, Pavlidis et al. present a mouse model of ascending U. parvum infection that resembles human disease, and show that mild cervical damage promotes intrauterine infection, inflammati...

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Autores principales:	Ioannis Pavlidis, Owen B. Spiller, Gabriella Sammut Demarco, Heather MacPherson, Sarah E. M. Howie, Jane E. Norman, Sarah J. Stock
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d709abe271f6429286256336780462eb
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spelling	oai:doaj.org-article:d709abe271f6429286256336780462eb2021-12-02T17:31:55ZCervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice10.1038/s41467-019-14089-y2041-1723https://doaj.org/article/d709abe271f6429286256336780462eb2020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-14089-yhttps://doaj.org/toc/2041-1723Ureaplasma parvum is often isolated from intrauterine infections, which are associated with 40% of preterm births. Here, Pavlidis et al. present a mouse model of ascending U. parvum infection that resembles human disease, and show that mild cervical damage promotes intrauterine infection, inflammation and preterm birth.Ioannis PavlidisOwen B. SpillerGabriella Sammut DemarcoHeather MacPhersonSarah E. M. HowieJane E. NormanSarah J. StockNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Ioannis Pavlidis Owen B. Spiller Gabriella Sammut Demarco Heather MacPherson Sarah E. M. Howie Jane E. Norman Sarah J. Stock Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
description	Ureaplasma parvum is often isolated from intrauterine infections, which are associated with 40% of preterm births. Here, Pavlidis et al. present a mouse model of ascending U. parvum infection that resembles human disease, and show that mild cervical damage promotes intrauterine infection, inflammation and preterm birth.
format	article
author	Ioannis Pavlidis Owen B. Spiller Gabriella Sammut Demarco Heather MacPherson Sarah E. M. Howie Jane E. Norman Sarah J. Stock
author_facet	Ioannis Pavlidis Owen B. Spiller Gabriella Sammut Demarco Heather MacPherson Sarah E. M. Howie Jane E. Norman Sarah J. Stock
author_sort	Ioannis Pavlidis
title	Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
title_short	Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
title_full	Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
title_fullStr	Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
title_full_unstemmed	Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
title_sort	cervical epithelial damage promotes ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d709abe271f6429286256336780462eb
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Cervical epithelial damage promotes Ureaplasma parvum ascending infection, intrauterine inflammation and preterm birth induction in mice

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