Placental transfer of maternally-derived IgA precludes the use of guthrie card eluates as a screening tool for primary immunodeficiency diseases.
There is a need for neonatal screening tools to improve the long-term clinical outcome of patients with primary immunodeficiency diseases (PID). Recently, a PCR-based screening method for both TRECs and KRECs using Guthrie card samples has been developed. However, the applicability of these excision...
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Autores principales: | Stephan Borte, Magdalena Janzi, Qiang Pan-Hammarström, Ulrika von Döbeln, Lennart Nordvall, Jacek Winiarski, Anders Fasth, Lennart Hammarström |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2012
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Materias: | |
Acceso en línea: | https://doaj.org/article/d70bc6bcd6c94972a023d332c4b174cc |
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