Placental transfer of maternally-derived IgA precludes the use of guthrie card eluates as a screening tool for primary immunodeficiency diseases.

There is a need for neonatal screening tools to improve the long-term clinical outcome of patients with primary immunodeficiency diseases (PID). Recently, a PCR-based screening method for both TRECs and KRECs using Guthrie card samples has been developed. However, the applicability of these excision...

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Auteurs principaux: Stephan Borte, Magdalena Janzi, Qiang Pan-Hammarström, Ulrika von Döbeln, Lennart Nordvall, Jacek Winiarski, Anders Fasth, Lennart Hammarström
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2012
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R
Q
Accès en ligne:https://doaj.org/article/d70bc6bcd6c94972a023d332c4b174cc
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