Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis

Abstract Background Osteoporosis (OP) is progressively becoming a global concern with the aging of the world’s populations. Osteoporotic fractures are associated with significantly increased mortality rates and a financial burden to health systems. This Meta-analysis aims to estimate the annual inci...

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Autores principales: Kiarash Tanha, Noushin Fahimfar, Shahrzad Nematollahi, Sayed Mahmoud Sajjadi-Jazi, Safoora Gharibzadeh, Mahnaz Sanjari, Kazem Khalagi, Fatemeh Hajivalizedeh, Alireza Raeisi, Bagher Larijani, Afshin Ostovar
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Publicado: BMC 2021
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spelling oai:doaj.org-article:d710fa20b6d04627b9c2e3d31228a6872021-12-05T12:07:34ZAnnual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis10.1186/s12877-021-02603-11471-2318https://doaj.org/article/d710fa20b6d04627b9c2e3d31228a6872021-11-01T00:00:00Zhttps://doi.org/10.1186/s12877-021-02603-1https://doaj.org/toc/1471-2318Abstract Background Osteoporosis (OP) is progressively becoming a global concern with the aging of the world’s populations. Osteoporotic fractures are associated with significantly increased mortality rates and a financial burden to health systems. This Meta-analysis aims to estimate the annual incidence of osteoporotic fractures in Iran. Methods A comprehensive systematic literature search was performed through Medline (PubMed), Embase, Scopus, Web of Science, and Google Scholar to identify studies which contain an investigation of the incidence of osteoporotic fractures in Iran up to December 3rd 2020, with no time and language restriction. For the risk of bias assessments of studies, the Joanna Briggs Institute (JBI) critical appraisal checklist for studies reporting prevalence data was used. The pooled estimation of the incidence of osteoporotic fractures in population aged≥50 years was calculated using random-effects meta-analysis, and the heterogeneity of included studies was quantified with the I2 statistic. Results In all, 6708 papers were initially retrieved from the electronic databases, among which seven studies were included in the meta-analysis. The pooled standardized annual cumulative incidence of hip fractures was estimated as 138.26 (95% CI: 98.71–193.65) per 100,000 population and 157.52 (95% CI: 124.29–199.64) per 100,000 population in men and women, respectively. Conclusion This study showed a high incidence rate of osteoporotic hip fractures in Iran. Early detection and treatment of individuals with higher risks of primary fragility fractures at primary health care as well as implementing fracture liaison services to prevent secondary fractures are highly recommended. The results suffer from the following limitations: first, a low number of studies that were eligible for inclusion; second, the lack of population-based studies; and presence of highly heterogeneous studies despite the use of a random effect model.Kiarash TanhaNoushin FahimfarShahrzad NematollahiSayed Mahmoud Sajjadi-JaziSafoora GharibzadehMahnaz SanjariKazem KhalagiFatemeh HajivalizedehAlireza RaeisiBagher LarijaniAfshin OstovarBMCarticleOsteoporosisOsteoporotic fracturesIncidenceIranMeta-analysisGeriatricsRC952-954.6ENBMC Geriatrics, Vol 21, Iss 1, Pp 1-8 (2021)
institution DOAJ
collection DOAJ
language EN
topic Osteoporosis
Osteoporotic fractures
Incidence
Iran
Meta-analysis
Geriatrics
RC952-954.6
spellingShingle Osteoporosis
Osteoporotic fractures
Incidence
Iran
Meta-analysis
Geriatrics
RC952-954.6
Kiarash Tanha
Noushin Fahimfar
Shahrzad Nematollahi
Sayed Mahmoud Sajjadi-Jazi
Safoora Gharibzadeh
Mahnaz Sanjari
Kazem Khalagi
Fatemeh Hajivalizedeh
Alireza Raeisi
Bagher Larijani
Afshin Ostovar
Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
description Abstract Background Osteoporosis (OP) is progressively becoming a global concern with the aging of the world’s populations. Osteoporotic fractures are associated with significantly increased mortality rates and a financial burden to health systems. This Meta-analysis aims to estimate the annual incidence of osteoporotic fractures in Iran. Methods A comprehensive systematic literature search was performed through Medline (PubMed), Embase, Scopus, Web of Science, and Google Scholar to identify studies which contain an investigation of the incidence of osteoporotic fractures in Iran up to December 3rd 2020, with no time and language restriction. For the risk of bias assessments of studies, the Joanna Briggs Institute (JBI) critical appraisal checklist for studies reporting prevalence data was used. The pooled estimation of the incidence of osteoporotic fractures in population aged≥50 years was calculated using random-effects meta-analysis, and the heterogeneity of included studies was quantified with the I2 statistic. Results In all, 6708 papers were initially retrieved from the electronic databases, among which seven studies were included in the meta-analysis. The pooled standardized annual cumulative incidence of hip fractures was estimated as 138.26 (95% CI: 98.71–193.65) per 100,000 population and 157.52 (95% CI: 124.29–199.64) per 100,000 population in men and women, respectively. Conclusion This study showed a high incidence rate of osteoporotic hip fractures in Iran. Early detection and treatment of individuals with higher risks of primary fragility fractures at primary health care as well as implementing fracture liaison services to prevent secondary fractures are highly recommended. The results suffer from the following limitations: first, a low number of studies that were eligible for inclusion; second, the lack of population-based studies; and presence of highly heterogeneous studies despite the use of a random effect model.
format article
author Kiarash Tanha
Noushin Fahimfar
Shahrzad Nematollahi
Sayed Mahmoud Sajjadi-Jazi
Safoora Gharibzadeh
Mahnaz Sanjari
Kazem Khalagi
Fatemeh Hajivalizedeh
Alireza Raeisi
Bagher Larijani
Afshin Ostovar
author_facet Kiarash Tanha
Noushin Fahimfar
Shahrzad Nematollahi
Sayed Mahmoud Sajjadi-Jazi
Safoora Gharibzadeh
Mahnaz Sanjari
Kazem Khalagi
Fatemeh Hajivalizedeh
Alireza Raeisi
Bagher Larijani
Afshin Ostovar
author_sort Kiarash Tanha
title Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
title_short Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
title_full Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
title_fullStr Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
title_full_unstemmed Annual incidence of osteoporotic hip fractures in Iran: a systematic review and meta-analysis
title_sort annual incidence of osteoporotic hip fractures in iran: a systematic review and meta-analysis
publisher BMC
publishDate 2021
url https://doaj.org/article/d710fa20b6d04627b9c2e3d31228a687
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