Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components

Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components

Daeshiho-tang (DSHT) is a traditional herbal formula consisting of six herbal medicines: <i>Bupleurum falcatum</i> L., <i>Scutellaria baicalensis</i> Georgi, <i>Paonia lactiflora</i> Pall., <i>Pheum palmatum</i> L., <i>Poncirus trifoliata</i&g...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Chang-Seob Seo, Hyeun-Kyoo Shin
Formato: article
Lenguaje:EN
Publicado: MDPI AG 2021
Materias:
simultaneous analysis
quality control
traditional herbal formula
daeshiho-tang
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Acceso en línea:https://doaj.org/article/d721740acad64cd3b97e5444421bfe96
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
id oai:doaj.org-article:d721740acad64cd3b97e5444421bfe96
record_format dspace
spelling oai:doaj.org-article:d721740acad64cd3b97e5444421bfe962021-11-11T15:17:08ZDevelopment of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components10.3390/app1121102422076-3417https://doaj.org/article/d721740acad64cd3b97e5444421bfe962021-11-01T00:00:00Zhttps://www.mdpi.com/2076-3417/11/21/10242https://doaj.org/toc/2076-3417Daeshiho-tang (DSHT) is a traditional herbal formula consisting of six herbal medicines: <i>Bupleurum falcatum</i> L., <i>Scutellaria baicalensis</i> Georgi, <i>Paonia lactiflora</i> Pall., <i>Pheum palmatum</i> L., <i>Poncirus trifoliata</i> (L.) Raf., and <i>Pinellia ternate</i> (Thunb.) Makino. In this study, we developed a simultaneous analysis method based on high-performance liquid chromatography for the quality control of DSHT. Chromatographic separation of 10 marker components (gallic acid, albiflorin, paeoniflorin, naringin, benzoic acid, baicalin, poncirin, wogonoside, baicalein, and wogonin) was achieved using a water–acetonitrile system as the mobile phase with a SunFire C18 reversed-phase column. The developed analytical method was validated with respect to linearity, limit of detection, limit of quantitation, recovery, and precision. Among the 10 markers of DSHT in the established assay, baicalin, the main compound of <i>Scutellaria baicalensis</i> Georgi, was present in the highest concentration (36.86–46.17 mg/g). The validated assay will be useful for the quality control of DSHT.Chang-Seob SeoHyeun-Kyoo ShinMDPI AGarticlesimultaneous analysisquality controltraditional herbal formuladaeshiho-tangTechnologyTEngineering (General). Civil engineering (General)TA1-2040Biology (General)QH301-705.5PhysicsQC1-999ChemistryQD1-999ENApplied Sciences, Vol 11, Iss 10242, p 10242 (2021)
institution DOAJ
collection DOAJ
language EN
topic simultaneous analysis
quality control
traditional herbal formula
daeshiho-tang
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
spellingShingle simultaneous analysis
quality control
traditional herbal formula
daeshiho-tang
Technology
T
Engineering (General). Civil engineering (General)
TA1-2040
Biology (General)
QH301-705.5
Physics
QC1-999
Chemistry
QD1-999
Chang-Seob Seo
Hyeun-Kyoo Shin
Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
description Daeshiho-tang (DSHT) is a traditional herbal formula consisting of six herbal medicines: <i>Bupleurum falcatum</i> L., <i>Scutellaria baicalensis</i> Georgi, <i>Paonia lactiflora</i> Pall., <i>Pheum palmatum</i> L., <i>Poncirus trifoliata</i> (L.) Raf., and <i>Pinellia ternate</i> (Thunb.) Makino. In this study, we developed a simultaneous analysis method based on high-performance liquid chromatography for the quality control of DSHT. Chromatographic separation of 10 marker components (gallic acid, albiflorin, paeoniflorin, naringin, benzoic acid, baicalin, poncirin, wogonoside, baicalein, and wogonin) was achieved using a water–acetonitrile system as the mobile phase with a SunFire C18 reversed-phase column. The developed analytical method was validated with respect to linearity, limit of detection, limit of quantitation, recovery, and precision. Among the 10 markers of DSHT in the established assay, baicalin, the main compound of <i>Scutellaria baicalensis</i> Georgi, was present in the highest concentration (36.86–46.17 mg/g). The validated assay will be useful for the quality control of DSHT.
format article
author Chang-Seob Seo
Hyeun-Kyoo Shin
author_facet Chang-Seob Seo
Hyeun-Kyoo Shin
author_sort Chang-Seob Seo
title Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
title_short Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
title_full Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
title_fullStr Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
title_full_unstemmed Development of a Simultaneous Analysis Method for Quality Control of a Traditional Herbal Formula, Daeshiho-Tang, Using 10 Marker Components
title_sort development of a simultaneous analysis method for quality control of a traditional herbal formula, daeshiho-tang, using 10 marker components
publisher MDPI AG
publishDate 2021
url https://doaj.org/article/d721740acad64cd3b97e5444421bfe96
work_keys_str_mv AT changseobseo developmentofasimultaneousanalysismethodforqualitycontrolofatraditionalherbalformuladaeshihotangusing10markercomponents
AT hyeunkyooshin developmentofasimultaneousanalysismethodforqualitycontrolofatraditionalherbalformuladaeshihotangusing10markercomponents
_version_ 1718435783536279552

Ejemplares similares