Early and intermediate age-related macular degeneration: update and clinical review

Alfredo García-Layana,1–3 Francisco Cabrera-López,4,5 José García-Arumí,6–8 Lluís Arias-Barquet,9,10 José M Ruiz-Moreno3,11,12 1Department of Ophthalmology, Clínica Universidad de Navarra, Pa...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	García-Layana A, Cabrera-López F, García-Arumí J, Arias-Barquet L, Ruiz-Moreno JM
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2017
Materias:	Age-related macular degeneration early AMD intermediate AMD risk factors classification prevention nutritional supplementation. Geriatrics RC952-954.6
Acceso en línea:	https://doaj.org/article/d731c77c78f34c34861df8da6f0fe0b4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d731c77c78f34c34861df8da6f0fe0b4
record_format	dspace
spelling	oai:doaj.org-article:d731c77c78f34c34861df8da6f0fe0b42021-12-02T01:36:38ZEarly and intermediate age-related macular degeneration: update and clinical review1178-1998https://doaj.org/article/d731c77c78f34c34861df8da6f0fe0b42017-10-01T00:00:00Zhttps://www.dovepress.com/early-and-intermediate-age-related-macular-degeneration-update-and-cli-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Alfredo García-Layana,1–3 Francisco Cabrera-López,4,5 José García-Arumí,6–8 Lluís Arias-Barquet,9,10 José M Ruiz-Moreno3,11,12 1Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain; 2Sociedad Española de Retina y Vítreo (SERV), Madrid, Spain; 3Red Telemática de Investigación Cooperativa Oftared, Instituto de Salud Carlos III, Madrid, Spain; 4Service of Ophthalmology, Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Las Palmas de Gran Canaria, Spain; 5Las Palmas Gran Canaria University, Las Palmas de Gran Canaria, Spain; 6Department of Retina and Vitreous, Instituto de Microcirugía Ocular (IMO), Barcelona, Spain; 7Department of Ophthalmology, Universidad Autónoma de Barcelona, Barcelona, Spain; 8Hospital Universitario Valle Hebrón, Barcelona, Spain; 9Section of Medical-Surgical Retina, Service of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain; 10University of Barcelona, Barcelona, Spain; 11Universidad Castilla-La Mancha, Albacete, Spain; 12Vissum Corporación Oftalmológica, Madrid, Spain Abstract: Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries. With the aging of population, AMD will become globally an increasingly important and prevalent disease worldwide. It is a complex disease whose etiology is associated with both genetic and environmental risk factors. An extensive decline in the quality of life and progressive need of daily living assistance resulting from AMD among those most severely affected highlights the essential role of preventive strategies, particularly advising patients to quit smoking. In addition, maintaining a healthy diet, controlling other risk factors (such as hypertension, obesity, and atherosclerosis), and the use of nutritional supplements (antioxidants) are recommendable. Genetic testing may be especially important in patients with a family history of AMD. Recently, unifying criteria for the clinical classification of AMD, defining no apparent aging changes; normal aging changes; and early, intermediate, and late AMD stages, are of value in predicting AMD risk of progression and in establishing recommendations for the diagnosis, therapeutic approach, and follow-up of patients. The present review is focused on early and intermediate AMD and presents a description of the clinical characteristics and ophthalmological findings for these stages, together with algorithms for the diagnosis and management of patients, which are easily applicable in daily clinical practice. Keywords: age-related macular degeneration, early AMD, intermediate AMD, risk factors, classification, prevention, nutritional supplementationGarcía-Layana ACabrera-López FGarcía-Arumí JArias-Barquet LRuiz-Moreno JMDove Medical PressarticleAge-related macular degenerationearly AMDintermediate AMDrisk factorsclassificationpreventionnutritional supplementation.GeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 12, Pp 1579-1587 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Age-related macular degeneration early AMD intermediate AMD risk factors classification prevention nutritional supplementation. Geriatrics RC952-954.6
spellingShingle	Age-related macular degeneration early AMD intermediate AMD risk factors classification prevention nutritional supplementation. Geriatrics RC952-954.6 García-Layana A Cabrera-López F García-Arumí J Arias-Barquet L Ruiz-Moreno JM Early and intermediate age-related macular degeneration: update and clinical review
description	Alfredo García-Layana,1–3 Francisco Cabrera-López,4,5 José García-Arumí,6–8 Lluís Arias-Barquet,9,10 José M Ruiz-Moreno3,11,12 1Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain; 2Sociedad Española de Retina y Vítreo (SERV), Madrid, Spain; 3Red Telemática de Investigación Cooperativa Oftared, Instituto de Salud Carlos III, Madrid, Spain; 4Service of Ophthalmology, Complejo Hospitalario Universitario Insular Materno-Infantil de Gran Canaria, Las Palmas de Gran Canaria, Spain; 5Las Palmas Gran Canaria University, Las Palmas de Gran Canaria, Spain; 6Department of Retina and Vitreous, Instituto de Microcirugía Ocular (IMO), Barcelona, Spain; 7Department of Ophthalmology, Universidad Autónoma de Barcelona, Barcelona, Spain; 8Hospital Universitario Valle Hebrón, Barcelona, Spain; 9Section of Medical-Surgical Retina, Service of Ophthalmology, Hospital Universitari de Bellvitge, Barcelona, Spain; 10University of Barcelona, Barcelona, Spain; 11Universidad Castilla-La Mancha, Albacete, Spain; 12Vissum Corporación Oftalmológica, Madrid, Spain Abstract: Age-related macular degeneration (AMD) is the leading cause of irreversible central vision loss in developed countries. With the aging of population, AMD will become globally an increasingly important and prevalent disease worldwide. It is a complex disease whose etiology is associated with both genetic and environmental risk factors. An extensive decline in the quality of life and progressive need of daily living assistance resulting from AMD among those most severely affected highlights the essential role of preventive strategies, particularly advising patients to quit smoking. In addition, maintaining a healthy diet, controlling other risk factors (such as hypertension, obesity, and atherosclerosis), and the use of nutritional supplements (antioxidants) are recommendable. Genetic testing may be especially important in patients with a family history of AMD. Recently, unifying criteria for the clinical classification of AMD, defining no apparent aging changes; normal aging changes; and early, intermediate, and late AMD stages, are of value in predicting AMD risk of progression and in establishing recommendations for the diagnosis, therapeutic approach, and follow-up of patients. The present review is focused on early and intermediate AMD and presents a description of the clinical characteristics and ophthalmological findings for these stages, together with algorithms for the diagnosis and management of patients, which are easily applicable in daily clinical practice. Keywords: age-related macular degeneration, early AMD, intermediate AMD, risk factors, classification, prevention, nutritional supplementation
format	article
author	García-Layana A Cabrera-López F García-Arumí J Arias-Barquet L Ruiz-Moreno JM
author_facet	García-Layana A Cabrera-López F García-Arumí J Arias-Barquet L Ruiz-Moreno JM
author_sort	García-Layana A
title	Early and intermediate age-related macular degeneration: update and clinical review
title_short	Early and intermediate age-related macular degeneration: update and clinical review
title_full	Early and intermediate age-related macular degeneration: update and clinical review
title_fullStr	Early and intermediate age-related macular degeneration: update and clinical review
title_full_unstemmed	Early and intermediate age-related macular degeneration: update and clinical review
title_sort	early and intermediate age-related macular degeneration: update and clinical review
publisher	Dove Medical Press
publishDate	2017
url	https://doaj.org/article/d731c77c78f34c34861df8da6f0fe0b4
work_keys_str_mv	AT garcialayanaa earlyandintermediateagerelatedmaculardegenerationupdateandclinicalreview AT cabreralopezf earlyandintermediateagerelatedmaculardegenerationupdateandclinicalreview AT garciaarumij earlyandintermediateagerelatedmaculardegenerationupdateandclinicalreview AT ariasbarquetl earlyandintermediateagerelatedmaculardegenerationupdateandclinicalreview AT ruizmorenojm earlyandintermediateagerelatedmaculardegenerationupdateandclinicalreview
_version_	1718402987706023936

Early and intermediate age-related macular degeneration: update and clinical review

Ejemplares similares