Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Vitamin A Metabolism by Dendritic Cells Triggers an Antimicrobial Response against <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Epidemiological evidence correlates low serum vitamin A (retinol) levels with increased susceptibility to active tuberculosis (TB); however, retinol is biologically inactive and must be converted into its bioactive form, all-trans retinoic acid (ATRA). Given that ATRA triggers a Niemann-Pic...

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Bibliographic Details
Main Authors: Elliot W. Kim, Avelino De Leon, Zhichun Jiang, Roxana A. Radu, Adrian R. Martineau, Edward D. Chan, Xiyuan Bai, Wen-Lin Su, Dennis J. Montoya, Robert L. Modlin, Philip T. Liu
Format: article
Language:EN
Published: American Society for Microbiology 2019
Subjects:
Mycobacterium tuberculosis
dendritic cells
transcellular metabolism
Microbiology
QR1-502
Online Access:https://doaj.org/article/d742d0149e544e31881c00788a5150dc
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