Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report

Background Data: Brown tumor is a lytic bone tumor and has variable symptoms according to the affected site. It is called brown because of its characteristic brown color believed to have occurred after accumulation of blood, fibrous tissue, and hemosiderin. Hyperparathyroidism can result in a brown...

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Autores principales:	Mohamed E Elsebaey, MD, Mohamed S Salman, MD., Mohamed Hassan Mahmoud, MD., Hassan Alshatoury*, MD., Amr AM Kamel, MD
Formato:	article
Lenguaje:	EN
Publicado:	Egyptian Spine Association 2019
Materias:	giant cell tumor lumbar spine brown tumor primary hyperparathyroidism Neurology. Diseases of the nervous system RC346-429
Acceso en línea:	https://doaj.org/article/d74ab9495f3b4f5fbedebb59aa816e56
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spelling	oai:doaj.org-article:d74ab9495f3b4f5fbedebb59aa816e562021-12-02T10:15:33ZBrown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report10.21608/esj.2020.10409.10932314-89502314-8969https://doaj.org/article/d74ab9495f3b4f5fbedebb59aa816e562019-10-01T00:00:00Zhttps://www.esj.journals.ekb.eg/article_80122_9bd11c8e4881a7e06cec1a0099bd2e7a.pdfhttps://doaj.org/toc/2314-8950https://doaj.org/toc/2314-8969Background Data: Brown tumor is a lytic bone tumor and has variable symptoms according to the affected site. It is called brown because of its characteristic brown color believed to have occurred after accumulation of blood, fibrous tissue, and hemosiderin. Hyperparathyroidism can result in a brown tumor whether it is primary or secondary, but this case is much rarer in primary hyperparathyroidism. It rarely affects the spine, while it is extremely rare to compromise the spinal canal. Purpose: To report a rare case of lumbar spinal brown tumor with primary hyperparathyroidism. Study Design: A case report of brown tumor of the lumbar spine (5th lumbar vertebrae). Patients and Methods: Our case was a forty-year-old female patient presenting with persistent dull aching low back pain. There was no history of any chronic illness. She had a 5-month history of slowly progressive left lower limb radicular pain and not associated with sphincter disturbance. Magnetic resonance imaging of the spine demonstrated lesion affecting the 5th lumbar vertebrae invading the left pedicle and compressing the spinal canal. Results: Team did neural decompression, biopsy harvesting, and partial corpectomy with reconstruction of the affected lumbar vertebra (L5) followed by fixation by rods and screws. The patient showed relief of the radicular pain and back pain on VAS. Histopathological analysis of the biopsy showed evidence of giant-cell tumor (brown tumor). Parathyroid survey was done and showed normal calcium levels. By revising the literature, we claim that this present study is reporting the 10th case of brown tumor of lumbar spine in patient with primary hyperparathyroidism. Conclusion: The diagnosis of brown tumor of spine could be considered in patients with lytic spine lesions. (2019ESJ192) Mohamed E Elsebaey, MDMohamed S Salman, MD.Mohamed Hassan Mahmoud, MD.Hassan Alshatoury*, MD.Amr AM Kamel, MDEgyptian Spine Associationarticlegiant cell tumorlumbar spinebrown tumorprimary hyperparathyroidismNeurology. Diseases of the nervous systemRC346-429ENEgyptian Spine Journal, Vol 32, Iss 1, Pp 64-68 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	giant cell tumor lumbar spine brown tumor primary hyperparathyroidism Neurology. Diseases of the nervous system RC346-429
spellingShingle	giant cell tumor lumbar spine brown tumor primary hyperparathyroidism Neurology. Diseases of the nervous system RC346-429 Mohamed E Elsebaey, MD Mohamed S Salman, MD. Mohamed Hassan Mahmoud, MD. Hassan Alshatoury*, MD. Amr AM Kamel, MD Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
description	Background Data: Brown tumor is a lytic bone tumor and has variable symptoms according to the affected site. It is called brown because of its characteristic brown color believed to have occurred after accumulation of blood, fibrous tissue, and hemosiderin. Hyperparathyroidism can result in a brown tumor whether it is primary or secondary, but this case is much rarer in primary hyperparathyroidism. It rarely affects the spine, while it is extremely rare to compromise the spinal canal. Purpose: To report a rare case of lumbar spinal brown tumor with primary hyperparathyroidism. Study Design: A case report of brown tumor of the lumbar spine (5th lumbar vertebrae). Patients and Methods: Our case was a forty-year-old female patient presenting with persistent dull aching low back pain. There was no history of any chronic illness. She had a 5-month history of slowly progressive left lower limb radicular pain and not associated with sphincter disturbance. Magnetic resonance imaging of the spine demonstrated lesion affecting the 5th lumbar vertebrae invading the left pedicle and compressing the spinal canal. Results: Team did neural decompression, biopsy harvesting, and partial corpectomy with reconstruction of the affected lumbar vertebra (L5) followed by fixation by rods and screws. The patient showed relief of the radicular pain and back pain on VAS. Histopathological analysis of the biopsy showed evidence of giant-cell tumor (brown tumor). Parathyroid survey was done and showed normal calcium levels. By revising the literature, we claim that this present study is reporting the 10th case of brown tumor of lumbar spine in patient with primary hyperparathyroidism. Conclusion: The diagnosis of brown tumor of spine could be considered in patients with lytic spine lesions. (2019ESJ192)
format	article
author	Mohamed E Elsebaey, MD Mohamed S Salman, MD. Mohamed Hassan Mahmoud, MD. Hassan Alshatoury*, MD. Amr AM Kamel, MD
author_facet	Mohamed E Elsebaey, MD Mohamed S Salman, MD. Mohamed Hassan Mahmoud, MD. Hassan Alshatoury*, MD. Amr AM Kamel, MD
author_sort	Mohamed E Elsebaey, MD
title	Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
title_short	Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
title_full	Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
title_fullStr	Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
title_full_unstemmed	Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report
title_sort	brown tumor of lumbar spine in a patient with primary hyperparathyroidism: case report
publisher	Egyptian Spine Association
publishDate	2019
url	https://doaj.org/article/d74ab9495f3b4f5fbedebb59aa816e56
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Brown Tumor of Lumbar Spine in a Patient with Primary Hyperparathyroidism: Case Report

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