The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.

<h4>Background</h4>Fetal growth restriction (FGR), defined as a fetus failing to reach its genetic growth potential, remains poorly diagnosed antenatally. This study aimed to assess the ability of continuous-wave Doppler ultrasound of the umbilical artery (CWD-UmA) to detect FGR in healt...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Ute Feucht, Helen Mulol, Valerie Vannevel, Robert Pattinson
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d74e76047e4a460e8700d7ed60d4d5b4
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:d74e76047e4a460e8700d7ed60d4d5b4
record_format	dspace
spelling	oai:doaj.org-article:d74e76047e4a460e8700d7ed60d4d5b42021-12-02T20:18:28ZThe ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.1932-620310.1371/journal.pone.0255960https://doaj.org/article/d74e76047e4a460e8700d7ed60d4d5b42021-01-01T00:00:00Zhttps://doi.org/10.1371/journal.pone.0255960https://doaj.org/toc/1932-6203<h4>Background</h4>Fetal growth restriction (FGR), defined as a fetus failing to reach its genetic growth potential, remains poorly diagnosed antenatally. This study aimed to assess the ability of continuous-wave Doppler ultrasound of the umbilical artery (CWD-UmA) to detect FGR in healthy women with low-risk pregnancies.<h4>Methods and findings</h4>This prospective longitudinal descriptive cohort study enrolled infants born to low-risk mothers who were screened with CWD-UmA between 28-34 weeks' gestation; the resistance index (RI) was classified as normal or abnormal. Infants were assessed at 6, 10, 14 weeks, and 6 months postnatally for anthropometric indicators and body composition using the deuterium dilution method to assess fat-free mass (FFM). Neonates in the abnormal RI group were compared with those in the normal RI group, and neonates classified as small-for-gestational age (SGA) were compared with appropriate-for-gestational age (AGA) neonates. Eighty-one term infants were included. Only 6 of 26 infants (23.1%) with an abnormal RI value would have been classified as SGA. The abnormal RI group had significantly reduced mean FFM and FFM-for-age Z-scores at 6, 10, 14 weeks, and 6 months compared with the normal RI group (P<0.015). The SGA group's FFM did not show this consistent trend when compared to AGA FFM, being significantly different only at 6 months (P = 0.039). The main limitation of the study was the small sample size of the infant follow-up.<h4>Conclusions</h4>Abnormal RI obtained from CWD-UmA is able to detect FGR and is considered a useful addition to classifying the neonate only by SGA or AGA at birth.Ute FeuchtHelen MulolValerie VannevelRobert PattinsonPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 8, p e0255960 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Ute Feucht Helen Mulol Valerie Vannevel Robert Pattinson The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
description	<h4>Background</h4>Fetal growth restriction (FGR), defined as a fetus failing to reach its genetic growth potential, remains poorly diagnosed antenatally. This study aimed to assess the ability of continuous-wave Doppler ultrasound of the umbilical artery (CWD-UmA) to detect FGR in healthy women with low-risk pregnancies.<h4>Methods and findings</h4>This prospective longitudinal descriptive cohort study enrolled infants born to low-risk mothers who were screened with CWD-UmA between 28-34 weeks' gestation; the resistance index (RI) was classified as normal or abnormal. Infants were assessed at 6, 10, 14 weeks, and 6 months postnatally for anthropometric indicators and body composition using the deuterium dilution method to assess fat-free mass (FFM). Neonates in the abnormal RI group were compared with those in the normal RI group, and neonates classified as small-for-gestational age (SGA) were compared with appropriate-for-gestational age (AGA) neonates. Eighty-one term infants were included. Only 6 of 26 infants (23.1%) with an abnormal RI value would have been classified as SGA. The abnormal RI group had significantly reduced mean FFM and FFM-for-age Z-scores at 6, 10, 14 weeks, and 6 months compared with the normal RI group (P<0.015). The SGA group's FFM did not show this consistent trend when compared to AGA FFM, being significantly different only at 6 months (P = 0.039). The main limitation of the study was the small sample size of the infant follow-up.<h4>Conclusions</h4>Abnormal RI obtained from CWD-UmA is able to detect FGR and is considered a useful addition to classifying the neonate only by SGA or AGA at birth.
format	article
author	Ute Feucht Helen Mulol Valerie Vannevel Robert Pattinson
author_facet	Ute Feucht Helen Mulol Valerie Vannevel Robert Pattinson
author_sort	Ute Feucht
title	The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
title_short	The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
title_full	The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
title_fullStr	The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
title_full_unstemmed	The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.
title_sort	ability of continuous-wave doppler ultrasound to detect fetal growth restriction.
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/d74e76047e4a460e8700d7ed60d4d5b4
work_keys_str_mv	AT utefeucht theabilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT helenmulol theabilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT valerievannevel theabilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT robertpattinson theabilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT utefeucht abilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT helenmulol abilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT valerievannevel abilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction AT robertpattinson abilityofcontinuouswavedopplerultrasoundtodetectfetalgrowthrestriction
_version_	1718374315477434368

The ability of continuous-wave Doppler ultrasound to detect fetal growth restriction.

Ejemplares similares