Pharmacological methods of therapy in Parkinson’s disease

The review concerns modern pharmacological methods of Parkinson's disease treatment. The basic drugs used in practice are levodopa, dopamine receptor agonists, MAO-B inhibitors, anticholinergics, COMT inhibitors, and amantadine drugs. The article considers main features, assessment methods and...

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Autores principales: Y. N. Bykov, T. B. Bender
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Lenguaje:RU
Publicado: Scientific Сentre for Family Health and Human Reproduction Problems 2016
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Acceso en línea:https://doaj.org/article/d7637ef0dae24212bac37b15159635d2
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spelling oai:doaj.org-article:d7637ef0dae24212bac37b15159635d22021-11-23T06:14:35ZPharmacological methods of therapy in Parkinson’s disease2541-94202587-959610.12737/21613https://doaj.org/article/d7637ef0dae24212bac37b15159635d22016-05-01T00:00:00Zhttps://www.actabiomedica.ru/jour/article/view/229https://doaj.org/toc/2541-9420https://doaj.org/toc/2587-9596The review concerns modern pharmacological methods of Parkinson's disease treatment. The basic drugs used in practice are levodopa, dopamine receptor agonists, MAO-B inhibitors, anticholinergics, COMT inhibitors, and amantadine drugs. The article considers main features, assessment methods and targets of the differentiated therapy, presents benefits and drawbacks of each drug, and describes the problem of generics. According to the study, there is a preferences to use long-acting drugs. The choice of a drug for Parkinson's disease treatment depends on such characteristics as the patient's age, the character of Parkinson's disease, the severity of movement disorder, concomitant diseases, the drug price, the patient's individual sensitivity to different drugs. Finally, the article presents recommendations on initial treatment of Parkinson's disease.Y. N. BykovT. B. BenderScientific Сentre for Family Health and Human Reproduction Problemsarticleparkinson's diseasepharmacological therapydopamineScienceQRUActa Biomedica Scientifica, Vol 1, Iss 3(1), Pp 65-71 (2016)
institution DOAJ
collection DOAJ
language RU
topic parkinson's disease
pharmacological therapy
dopamine
Science
Q
spellingShingle parkinson's disease
pharmacological therapy
dopamine
Science
Q
Y. N. Bykov
T. B. Bender
Pharmacological methods of therapy in Parkinson’s disease
description The review concerns modern pharmacological methods of Parkinson's disease treatment. The basic drugs used in practice are levodopa, dopamine receptor agonists, MAO-B inhibitors, anticholinergics, COMT inhibitors, and amantadine drugs. The article considers main features, assessment methods and targets of the differentiated therapy, presents benefits and drawbacks of each drug, and describes the problem of generics. According to the study, there is a preferences to use long-acting drugs. The choice of a drug for Parkinson's disease treatment depends on such characteristics as the patient's age, the character of Parkinson's disease, the severity of movement disorder, concomitant diseases, the drug price, the patient's individual sensitivity to different drugs. Finally, the article presents recommendations on initial treatment of Parkinson's disease.
format article
author Y. N. Bykov
T. B. Bender
author_facet Y. N. Bykov
T. B. Bender
author_sort Y. N. Bykov
title Pharmacological methods of therapy in Parkinson’s disease
title_short Pharmacological methods of therapy in Parkinson’s disease
title_full Pharmacological methods of therapy in Parkinson’s disease
title_fullStr Pharmacological methods of therapy in Parkinson’s disease
title_full_unstemmed Pharmacological methods of therapy in Parkinson’s disease
title_sort pharmacological methods of therapy in parkinson’s disease
publisher Scientific Сentre for Family Health and Human Reproduction Problems
publishDate 2016
url https://doaj.org/article/d7637ef0dae24212bac37b15159635d2
work_keys_str_mv AT ynbykov pharmacologicalmethodsoftherapyinparkinsonsdisease
AT tbbender pharmacologicalmethodsoftherapyinparkinsonsdisease
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