A computational framework to study sub-cellular RNA localization

Automated analysis of RNA localisation in smFISH data has been elusive. Here, the authors simulate and use a large dataset of images to design and validate a framework for highly accurate classification of sub-cellular RNA localisation patterns from smFISH experiments.

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Autores principales: Aubin Samacoits, Racha Chouaib, Adham Safieddine, Abdel-Meneem Traboulsi, Wei Ouyang, Christophe Zimmer, Marion Peter, Edouard Bertrand, Thomas Walter, Florian Mueller
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/d764029d18694212956189e233896653
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spelling oai:doaj.org-article:d764029d18694212956189e2338966532021-12-02T14:39:05ZA computational framework to study sub-cellular RNA localization10.1038/s41467-018-06868-w2041-1723https://doaj.org/article/d764029d18694212956189e2338966532018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06868-whttps://doaj.org/toc/2041-1723Automated analysis of RNA localisation in smFISH data has been elusive. Here, the authors simulate and use a large dataset of images to design and validate a framework for highly accurate classification of sub-cellular RNA localisation patterns from smFISH experiments.Aubin SamacoitsRacha ChouaibAdham SafieddineAbdel-Meneem TraboulsiWei OuyangChristophe ZimmerMarion PeterEdouard BertrandThomas WalterFlorian MuellerNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Aubin Samacoits
Racha Chouaib
Adham Safieddine
Abdel-Meneem Traboulsi
Wei Ouyang
Christophe Zimmer
Marion Peter
Edouard Bertrand
Thomas Walter
Florian Mueller
A computational framework to study sub-cellular RNA localization
description Automated analysis of RNA localisation in smFISH data has been elusive. Here, the authors simulate and use a large dataset of images to design and validate a framework for highly accurate classification of sub-cellular RNA localisation patterns from smFISH experiments.
format article
author Aubin Samacoits
Racha Chouaib
Adham Safieddine
Abdel-Meneem Traboulsi
Wei Ouyang
Christophe Zimmer
Marion Peter
Edouard Bertrand
Thomas Walter
Florian Mueller
author_facet Aubin Samacoits
Racha Chouaib
Adham Safieddine
Abdel-Meneem Traboulsi
Wei Ouyang
Christophe Zimmer
Marion Peter
Edouard Bertrand
Thomas Walter
Florian Mueller
author_sort Aubin Samacoits
title A computational framework to study sub-cellular RNA localization
title_short A computational framework to study sub-cellular RNA localization
title_full A computational framework to study sub-cellular RNA localization
title_fullStr A computational framework to study sub-cellular RNA localization
title_full_unstemmed A computational framework to study sub-cellular RNA localization
title_sort computational framework to study sub-cellular rna localization
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/d764029d18694212956189e233896653
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