Post-conception heat exposure increases clinically unobserved pregnancy losses

Abstract Evidence of the relationship between temperature during pregnancy and human embryo mortality is limited. Most importantly, the literature lacks causal estimations and studies on early pregnancy losses. Here, we estimate the impact of early pregnancy temperature exposure on the clinically un...

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Autores principales:	Tamás Hajdu, Gábor Hajdu
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/d7735cf024964dde91f823b4546ada1d
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spelling	oai:doaj.org-article:d7735cf024964dde91f823b4546ada1d2021-12-02T13:48:41ZPost-conception heat exposure increases clinically unobserved pregnancy losses10.1038/s41598-021-81496-x2045-2322https://doaj.org/article/d7735cf024964dde91f823b4546ada1d2021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81496-xhttps://doaj.org/toc/2045-2322Abstract Evidence of the relationship between temperature during pregnancy and human embryo mortality is limited. Most importantly, the literature lacks causal estimations and studies on early pregnancy losses. Here, we estimate the impact of early pregnancy temperature exposure on the clinically unobserved pregnancy loss rate. We use administrative data of clinically observed pregnancies from more than three decades for Hungary. We apply an empirical approach that allows us to infer the impact of temperature on the clinically unobserved pregnancy loss rate from the estimated effects on the clinically observed conception rate. The results show that exposure to hot temperatures during the first few weeks after the conception week increases the clinically unobserved pregnancy loss rate, whereas exposure to colder temperatures seems to decrease it. Importantly, the temperature-induced changes represent changes in the total number of pregnancy losses rather than a compositional change between clinically observed and clinically unobserved pregnancy losses.Tamás HajduGábor HajduNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Tamás Hajdu Gábor Hajdu Post-conception heat exposure increases clinically unobserved pregnancy losses
description	Abstract Evidence of the relationship between temperature during pregnancy and human embryo mortality is limited. Most importantly, the literature lacks causal estimations and studies on early pregnancy losses. Here, we estimate the impact of early pregnancy temperature exposure on the clinically unobserved pregnancy loss rate. We use administrative data of clinically observed pregnancies from more than three decades for Hungary. We apply an empirical approach that allows us to infer the impact of temperature on the clinically unobserved pregnancy loss rate from the estimated effects on the clinically observed conception rate. The results show that exposure to hot temperatures during the first few weeks after the conception week increases the clinically unobserved pregnancy loss rate, whereas exposure to colder temperatures seems to decrease it. Importantly, the temperature-induced changes represent changes in the total number of pregnancy losses rather than a compositional change between clinically observed and clinically unobserved pregnancy losses.
format	article
author	Tamás Hajdu Gábor Hajdu
author_facet	Tamás Hajdu Gábor Hajdu
author_sort	Tamás Hajdu
title	Post-conception heat exposure increases clinically unobserved pregnancy losses
title_short	Post-conception heat exposure increases clinically unobserved pregnancy losses
title_full	Post-conception heat exposure increases clinically unobserved pregnancy losses
title_fullStr	Post-conception heat exposure increases clinically unobserved pregnancy losses
title_full_unstemmed	Post-conception heat exposure increases clinically unobserved pregnancy losses
title_sort	post-conception heat exposure increases clinically unobserved pregnancy losses
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/d7735cf024964dde91f823b4546ada1d
work_keys_str_mv	AT tamashajdu postconceptionheatexposureincreasesclinicallyunobservedpregnancylosses AT gaborhajdu postconceptionheatexposureincreasesclinicallyunobservedpregnancylosses
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Post-conception heat exposure increases clinically unobserved pregnancy losses

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