Activation of nuclear factor-kappa B by TNF promotes nucleus pulposus mineralization through inhibition of ANKH and ENPP1

Abstract Spontaneous mineralization of the nucleus pulposus (NP) has been observed in cases of intervertebral disc degeneration (IDD). Inflammatory cytokines have been implicated in mineralization of multiple tissues through their modulation of expression of factors that enable or inhibit mineraliza...

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Autores principales: Agata K. Krzyzanowska, Robert J. Frawley, Sheela Damle, Tony Chen, Miguel Otero, Matthew E. Cunningham
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/d774118d3da34834890dc5881ee8e16d
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