Type I interferon sensing unlocks dormant adipocyte inflammatory potential

White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipocyte phenotype.

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Autores principales:	Calvin C. Chan, Michelle S. M. A. Damen, Maria E. Moreno-Fernandez, Traci E. Stankiewicz, Monica Cappelletti, Pablo C. Alarcon, Jarren R. Oates, Jessica R. Doll, Rajib Mukherjee, Xiaoting Chen, Rebekah Karns, Matthew T. Weirauch, Michael A. Helmrath, Thomas H. Inge, Senad Divanovic
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/d7769e000a41416a858c145b467956f7
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spelling	oai:doaj.org-article:d7769e000a41416a858c145b467956f72021-12-02T15:56:39ZType I interferon sensing unlocks dormant adipocyte inflammatory potential10.1038/s41467-020-16571-42041-1723https://doaj.org/article/d7769e000a41416a858c145b467956f72020-06-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-16571-4https://doaj.org/toc/2041-1723White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipocyte phenotype.Calvin C. ChanMichelle S. M. A. DamenMaria E. Moreno-FernandezTraci E. StankiewiczMonica CappellettiPablo C. AlarconJarren R. OatesJessica R. DollRajib MukherjeeXiaoting ChenRebekah KarnsMatthew T. WeirauchMichael A. HelmrathThomas H. IngeSenad DivanovicNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Calvin C. Chan Michelle S. M. A. Damen Maria E. Moreno-Fernandez Traci E. Stankiewicz Monica Cappelletti Pablo C. Alarcon Jarren R. Oates Jessica R. Doll Rajib Mukherjee Xiaoting Chen Rebekah Karns Matthew T. Weirauch Michael A. Helmrath Thomas H. Inge Senad Divanovic Type I interferon sensing unlocks dormant adipocyte inflammatory potential
description	White adipose inflammation can occur in obesity and is at least in part mediated by inflammatory immune cells. Here the authors show that the Type I Interferon/Interferon alpha-beta receptor axis promotes an inflammatory, glycolysis associated adipocyte phenotype.
format	article
author	Calvin C. Chan Michelle S. M. A. Damen Maria E. Moreno-Fernandez Traci E. Stankiewicz Monica Cappelletti Pablo C. Alarcon Jarren R. Oates Jessica R. Doll Rajib Mukherjee Xiaoting Chen Rebekah Karns Matthew T. Weirauch Michael A. Helmrath Thomas H. Inge Senad Divanovic
author_facet	Calvin C. Chan Michelle S. M. A. Damen Maria E. Moreno-Fernandez Traci E. Stankiewicz Monica Cappelletti Pablo C. Alarcon Jarren R. Oates Jessica R. Doll Rajib Mukherjee Xiaoting Chen Rebekah Karns Matthew T. Weirauch Michael A. Helmrath Thomas H. Inge Senad Divanovic
author_sort	Calvin C. Chan
title	Type I interferon sensing unlocks dormant adipocyte inflammatory potential
title_short	Type I interferon sensing unlocks dormant adipocyte inflammatory potential
title_full	Type I interferon sensing unlocks dormant adipocyte inflammatory potential
title_fullStr	Type I interferon sensing unlocks dormant adipocyte inflammatory potential
title_full_unstemmed	Type I interferon sensing unlocks dormant adipocyte inflammatory potential
title_sort	type i interferon sensing unlocks dormant adipocyte inflammatory potential
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/d7769e000a41416a858c145b467956f7
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Type I interferon sensing unlocks dormant adipocyte inflammatory potential

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