ATP release during cell swelling activates a Ca2+-dependent Cl− current by autocrine mechanism in mouse hippocampal microglia

Abstract Microglia cells, resident immune cells of the brain, survey brain parenchyma by dynamically extending and retracting their processes. Cl− channels, activated in the cellular response to stretch/swelling, take part in several functions deeply connected with microglia physiology, including ce...

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Autores principales: E. Murana, F. Pagani, B. Basilico, M. Sundukova, L. Batti, S. Di Angelantonio, B. Cortese, A. Grimaldi, A. Francioso, P. Heppenstall, P. Bregestovski, C. Limatola, D. Ragozzino
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/d77ebf08d06c4d1b83ceb109bfaf6f96
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