Paf1 and Ctr9 subcomplex formation is essential for Paf1 complex assembly and functional regulation
The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex plays an essential role in gene regulation. Here, the authors report two structures of the human and yeast Ctr9/Paf1 subcomplexes, and find that this is essential for Paf1 complex assembly and function.
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| Autores principales: | , , , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2018
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/d788840a7dc24897813c51ea585601c8 |
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| Sumario: | The evolutionarily conserved multifunctional polymerase-associated factor 1 (Paf1) complex plays an essential role in gene regulation. Here, the authors report two structures of the human and yeast Ctr9/Paf1 subcomplexes, and find that this is essential for Paf1 complex assembly and function. |
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