Optogenetic engineering to probe the molecular choreography of STIM1-mediated cell signaling

Optogenetic tools have been used to control cellular behaviours but their use to probe structure-function relations of signalling proteins are underexplored. Here the authors engineer optogenetic modules into STIM1 to dissect molecular details of STIM1-mediated signalling and control various cellula...

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Autores principales: Guolin Ma, Lian He, Shuzhong Liu, Jiansheng Xie, Zixian Huang, Ji Jing, Yi-Tsang Lee, Rui Wang, Hesheng Luo, Weidong Han, Yun Huang, Yubin Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/d794e4ce185f4e5981a7283cbeabcec0
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