In situ structures of rotavirus polymerase in action and mechanism of mRNA transcription and release

Rotaviruses are of great medical significance because they cause gastroenteritis in children. Here the authors provide insights into the mechanism of viral mRNA transcription by determining the in situ cryo-EM structures of a working rotavirus’ RNA-dependent-RNA polymerase, which is of interest for...

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Autores principales: Ke Ding, Cristina C. Celma, Xing Zhang, Thomas Chang, Wesley Shen, Ivo Atanasov, Polly Roy, Z. Hong Zhou
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d7ab0cfbd1d642369d08a8a85f7cd652
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