Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?

Lactate constitutes the primary gluconeogenic precursor in healthy humans at rest and during low-intensity exercise. Data on the interactions between lactate and glucose metabolisms during recovery after short-duration high-intensity exercise are sparse. The aim of the present study was to describe...

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Autores principales:	Laurent A. Messonnier, Benjamin Chatel, Chi-An W. Emhoff, Léo Blervaque, Samuel Oyono-Enguéllé
Formato:	article
Lenguaje:	EN
Publicado:	Frontiers Media S.A. 2021
Materias:	lactate glucose recovery gluconeogenesis liver Nutrition. Foods and food supply TX341-641
Acceso en línea:	https://doaj.org/article/d7ade0cd2ef7468b8886e9180c4bd28f
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spelling	oai:doaj.org-article:d7ade0cd2ef7468b8886e9180c4bd28f2021-11-11T10:21:56ZDelayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?2296-861X10.3389/fnut.2021.734152https://doaj.org/article/d7ade0cd2ef7468b8886e9180c4bd28f2021-11-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fnut.2021.734152/fullhttps://doaj.org/toc/2296-861XLactate constitutes the primary gluconeogenic precursor in healthy humans at rest and during low-intensity exercise. Data on the interactions between lactate and glucose metabolisms during recovery after short-duration high-intensity exercise are sparse. The aim of the present study was to describe blood glucose ([glucose]b) and lactate ([lactate]b) concentration curves during recovery following short-duration high-intensity exercise. Fifteen healthy Cameroonian subjects took part in the study and performed successively (i) an incremental exercise to exhaustion to determine maximal work rate (Pmax) and (ii) a 2-min 110% Pmax exercise after which blood lactate and glucose concentrations were measured during the 80-min passive recovery. In response to the 2-min 110% Pmax exercise, [glucose]b remained stable (from 4.93 ± 1.13 to 4.65 ± 0.74 mmol.L−1, NS) while [lactate]b increased (from 1.35 ± 0.36 to 7.87 ± 1.66 mmol.L−1, p < 0.0001). During recovery, blood lactate concentrations displayed the classic biphasic curve while blood glucose concentrations displayed a singular shape including a delayed and transitory rebound of glycemia. This rebound began at 27.7 ± 6.2 min and peaked at 6.78 ± 0.53 mmol.L−1 at 56.3 ± 9.7 min into recovery. The area under the curve (AUC) of [lactate]b during the rebound of glycemia was positively correlated with the peak value of glycemia and the AUC of [glucose]b during the rebound. In conclusion, the delayed rebound of glycemia observed in the present study was associated with lactate availability during this period.Laurent A. MessonnierBenjamin ChatelChi-An W. EmhoffLéo BlervaqueSamuel Oyono-EnguélléFrontiers Media S.A.articlelactateglucoserecoverygluconeogenesisliverNutrition. Foods and food supplyTX341-641ENFrontiers in Nutrition, Vol 8 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	lactate glucose recovery gluconeogenesis liver Nutrition. Foods and food supply TX341-641
spellingShingle	lactate glucose recovery gluconeogenesis liver Nutrition. Foods and food supply TX341-641 Laurent A. Messonnier Benjamin Chatel Chi-An W. Emhoff Léo Blervaque Samuel Oyono-Enguéllé Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
description	Lactate constitutes the primary gluconeogenic precursor in healthy humans at rest and during low-intensity exercise. Data on the interactions between lactate and glucose metabolisms during recovery after short-duration high-intensity exercise are sparse. The aim of the present study was to describe blood glucose ([glucose]b) and lactate ([lactate]b) concentration curves during recovery following short-duration high-intensity exercise. Fifteen healthy Cameroonian subjects took part in the study and performed successively (i) an incremental exercise to exhaustion to determine maximal work rate (Pmax) and (ii) a 2-min 110% Pmax exercise after which blood lactate and glucose concentrations were measured during the 80-min passive recovery. In response to the 2-min 110% Pmax exercise, [glucose]b remained stable (from 4.93 ± 1.13 to 4.65 ± 0.74 mmol.L−1, NS) while [lactate]b increased (from 1.35 ± 0.36 to 7.87 ± 1.66 mmol.L−1, p < 0.0001). During recovery, blood lactate concentrations displayed the classic biphasic curve while blood glucose concentrations displayed a singular shape including a delayed and transitory rebound of glycemia. This rebound began at 27.7 ± 6.2 min and peaked at 6.78 ± 0.53 mmol.L−1 at 56.3 ± 9.7 min into recovery. The area under the curve (AUC) of [lactate]b during the rebound of glycemia was positively correlated with the peak value of glycemia and the AUC of [glucose]b during the rebound. In conclusion, the delayed rebound of glycemia observed in the present study was associated with lactate availability during this period.
format	article
author	Laurent A. Messonnier Benjamin Chatel Chi-An W. Emhoff Léo Blervaque Samuel Oyono-Enguéllé
author_facet	Laurent A. Messonnier Benjamin Chatel Chi-An W. Emhoff Léo Blervaque Samuel Oyono-Enguéllé
author_sort	Laurent A. Messonnier
title	Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
title_short	Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
title_full	Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
title_fullStr	Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
title_full_unstemmed	Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?
title_sort	delayed rebound of glycemia during recovery following short-duration high-intensity exercise: are there lactate and glucose metabolism interactions?
publisher	Frontiers Media S.A.
publishDate	2021
url	https://doaj.org/article/d7ade0cd2ef7468b8886e9180c4bd28f
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Delayed Rebound of Glycemia During Recovery Following Short-Duration High-Intensity Exercise: Are There Lactate and Glucose Metabolism Interactions?

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