Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs
The precise relationship between neurobehavioural effects and neurotransmitter effects of psychiatric drugs are not always understood. Here the authors develop a database documenting the neurotransmitter response in rats to 258 different neuropsychiatric drugs, and conclude that this neurotransmitte...
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Nature Portfolio
2018
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oai:doaj.org-article:d7b1a3592d6d4e2087b019333a9fb4e32021-12-02T14:40:31ZSystemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs10.1038/s41467-018-07239-12041-1723https://doaj.org/article/d7b1a3592d6d4e2087b019333a9fb4e32018-11-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-07239-1https://doaj.org/toc/2041-1723The precise relationship between neurobehavioural effects and neurotransmitter effects of psychiatric drugs are not always understood. Here the authors develop a database documenting the neurotransmitter response in rats to 258 different neuropsychiatric drugs, and conclude that this neurotransmitter response does not, in general, reflect the current categorisation of those drugs.Hamid R. NooriLewis H. MervinVahid BokharaieÖzlem DurmusLisamon EgenriederStefan FritzeBritta GruhlkeGiulia ReinhardtHans-Hendrik SchabelSabine StaudenmaierNikos K. LogothetisAndreas BenderRainer SpanagelNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-14 (2018) |
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Science Q |
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Science Q Hamid R. Noori Lewis H. Mervin Vahid Bokharaie Özlem Durmus Lisamon Egenrieder Stefan Fritze Britta Gruhlke Giulia Reinhardt Hans-Hendrik Schabel Sabine Staudenmaier Nikos K. Logothetis Andreas Bender Rainer Spanagel Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
description |
The precise relationship between neurobehavioural effects and neurotransmitter effects of psychiatric drugs are not always understood. Here the authors develop a database documenting the neurotransmitter response in rats to 258 different neuropsychiatric drugs, and conclude that this neurotransmitter response does not, in general, reflect the current categorisation of those drugs. |
format |
article |
author |
Hamid R. Noori Lewis H. Mervin Vahid Bokharaie Özlem Durmus Lisamon Egenrieder Stefan Fritze Britta Gruhlke Giulia Reinhardt Hans-Hendrik Schabel Sabine Staudenmaier Nikos K. Logothetis Andreas Bender Rainer Spanagel |
author_facet |
Hamid R. Noori Lewis H. Mervin Vahid Bokharaie Özlem Durmus Lisamon Egenrieder Stefan Fritze Britta Gruhlke Giulia Reinhardt Hans-Hendrik Schabel Sabine Staudenmaier Nikos K. Logothetis Andreas Bender Rainer Spanagel |
author_sort |
Hamid R. Noori |
title |
Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
title_short |
Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
title_full |
Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
title_fullStr |
Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
title_full_unstemmed |
Systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
title_sort |
systemic neurotransmitter responses to clinically approved and experimental neuropsychiatric drugs |
publisher |
Nature Portfolio |
publishDate |
2018 |
url |
https://doaj.org/article/d7b1a3592d6d4e2087b019333a9fb4e3 |
work_keys_str_mv |
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