What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during...
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Radcliffe Medical Media
2021
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oai:doaj.org-article:d7b1cf4514ae4df7ac47249d3c48bfdf2021-12-04T16:04:36ZWhat an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries10.15420/icr.2021.101756-14851756-1477https://doaj.org/article/d7b1cf4514ae4df7ac47249d3c48bfdf2021-06-01T00:00:00Zhttps://icrjournal.com/articleindex/icr.2021.10https://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway.Robert SykesDaniel DohertyKenneth MangionAndrew MorrowColin BerryRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 16, Iss , Pp - (2021) |
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Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 |
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Surgery RD1-811 Diseases of the circulatory (Cardiovascular) system RC666-701 Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
description |
MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway. |
format |
article |
author |
Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry |
author_facet |
Robert Sykes Daniel Doherty Kenneth Mangion Andrew Morrow Colin Berry |
author_sort |
Robert Sykes |
title |
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
title_short |
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
title_full |
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
title_fullStr |
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
title_full_unstemmed |
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries |
title_sort |
what an interventionalist needs to know about mi with non-obstructive coronary arteries |
publisher |
Radcliffe Medical Media |
publishDate |
2021 |
url |
https://doaj.org/article/d7b1cf4514ae4df7ac47249d3c48bfdf |
work_keys_str_mv |
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