What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries

MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during...

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Autores principales: Robert Sykes, Daniel Doherty, Kenneth Mangion, Andrew Morrow, Colin Berry
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Lenguaje:EN
Publicado: Radcliffe Medical Media 2021
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Acceso en línea:https://doaj.org/article/d7b1cf4514ae4df7ac47249d3c48bfdf
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spelling oai:doaj.org-article:d7b1cf4514ae4df7ac47249d3c48bfdf2021-12-04T16:04:36ZWhat an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries10.15420/icr.2021.101756-14851756-1477https://doaj.org/article/d7b1cf4514ae4df7ac47249d3c48bfdf2021-06-01T00:00:00Zhttps://icrjournal.com/articleindex/icr.2021.10https://doaj.org/toc/1756-1477https://doaj.org/toc/1756-1485MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway.Robert SykesDaniel DohertyKenneth MangionAndrew MorrowColin BerryRadcliffe Medical MediaarticleSurgeryRD1-811Diseases of the circulatory (Cardiovascular) systemRC666-701ENInterventional Cardiology: Reviews, Research, Resources, Vol 16, Iss , Pp - (2021)
institution DOAJ
collection DOAJ
language EN
topic Surgery
RD1-811
Diseases of the circulatory (Cardiovascular) system
RC666-701
spellingShingle Surgery
RD1-811
Diseases of the circulatory (Cardiovascular) system
RC666-701
Robert Sykes
Daniel Doherty
Kenneth Mangion
Andrew Morrow
Colin Berry
What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
description MI with non-obstructive coronary arteries (MINOCA) is caused by a heterogeneous group of vascular or myocardial disorders. MINOCA occurs in 5–15% of patients presenting with acute ST-segment elevation MI or non-ST segment elevation MI and prognosis is impaired. The diagnosis of MINOCA is made during coronary angiography following acute MI, where there is no stenosis ≥50% present in an infarct-related epicardial artery and no overt systemic aetiology for the presentation. Accurate diagnosis and subsequent management require the appropriate utilisation of intravascular imaging, coronary function testing and subsequent imaging to assess for myocardial disorders without coronary involvement. Although plaque-related MINOCA is currently managed with empirical secondary prevention strategies, there remains an unmet therapeutic need for targeted and evidence-based therapy for MINOCA patients and increased awareness of the recommended diagnostic pathway.
format article
author Robert Sykes
Daniel Doherty
Kenneth Mangion
Andrew Morrow
Colin Berry
author_facet Robert Sykes
Daniel Doherty
Kenneth Mangion
Andrew Morrow
Colin Berry
author_sort Robert Sykes
title What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
title_short What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
title_full What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
title_fullStr What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
title_full_unstemmed What an Interventionalist Needs to Know About MI with Non-obstructive Coronary Arteries
title_sort what an interventionalist needs to know about mi with non-obstructive coronary arteries
publisher Radcliffe Medical Media
publishDate 2021
url https://doaj.org/article/d7b1cf4514ae4df7ac47249d3c48bfdf
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