Understanding the influence of lipid bilayers and ligand molecules in determining the conformational dynamics of somatostatin receptor 2
Abstract Somatostatin receptor 2 (SSTR2) is a G-protein coupled receptor (GPCR) that controls numerous cellular processes including cell-to-cell signaling. In this study, we report how the lipid and ligand molecules influence the conformational dynamics of the membrane-bound SSTR2. Molecular simulat...
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Autores principales: | Santhosh Kumar Nagarajan, Sathya Babu, Seema A. Kulkarni, Aanand Vadivelu, Panneer Devaraju, Honglae Sohn, Thirumurthy Madhavan |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2021
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Materias: | |
Acceso en línea: | https://doaj.org/article/d7b23b4ad2684bf38c546fb52cba4cdb |
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