Understanding the influence of lipid bilayers and ligand molecules in determining the conformational dynamics of somatostatin receptor 2

Abstract Somatostatin receptor 2 (SSTR2) is a G-protein coupled receptor (GPCR) that controls numerous cellular processes including cell-to-cell signaling. In this study, we report how the lipid and ligand molecules influence the conformational dynamics of the membrane-bound SSTR2. Molecular simulat...

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Bibliographic Details
Main Authors: Santhosh Kumar Nagarajan, Sathya Babu, Seema A. Kulkarni, Aanand Vadivelu, Panneer Devaraju, Honglae Sohn, Thirumurthy Madhavan
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
R
Q
Online Access:https://doaj.org/article/d7b23b4ad2684bf38c546fb52cba4cdb
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