Cold-induction of afadin in brown fat supports its thermogenic capacity
Abstract The profound energy-expending nature of brown adipose tissue (BAT) thermogenesis makes it an attractive target tissue to combat obesity-associated metabolic disorders. While cold exposure is the strongest inducer of BAT activity, the temporal mechanisms tuning BAT adaptation during this act...
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Main Authors: | Morten Lundh, Ali Altıntaş, Marco Tozzi, Odile Fabre, Tao Ma, Farnaz Shamsi, Zachary Gerhart-Hines, Romain Barrès, Yu-Hua Tseng, Brice Emanuelli |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Online Access: | https://doaj.org/article/d7c56c917a264bc39cc895ee89f8c7c9 |
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