XPC is an RNA polymerase II cofactor recruiting ATAC to promoters by interacting with E2F1

XPC plays an important role in the nuclear exicision repair pathways. Here the authors show that in addition, XPC plays a role in transcription regulation by interacting with KAT2A and E2F1 and recruiting the ATAC coactivator complex to promoters.

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Auteurs principaux: B. Bidon, I. Iltis, M. Semer, Z. Nagy, A. Larnicol, A. Cribier, M. Benkirane, F. Coin, J-M. Egly, N. Le May
Format: article
Langue:EN
Publié: Nature Portfolio 2018
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Accès en ligne:https://doaj.org/article/d7c88e12cd25418f9f593140142c4d3f
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