Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe

In addition to serotonin neurons, the dorsal raphe nucleus (DR) also contains dopamine, glutamate, and GABA neurons. Here, the authors systematically compare the neurochemical identity, cell type specificity, anatomical distribution, and connectivity of DR cells targeted by commonly used Cre lines.

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Autores principales: Daniel F. Cardozo Pinto, Hongbin Yang, Iskra Pollak Dorocic, Johannes W. de Jong, Vivian J. Han, James R. Peck, Yichen Zhu, Christine Liu, Kevin T. Beier, Marten P. Smidt, Stephan Lammel
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2019
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Acceso en línea:https://doaj.org/article/d7cb546281f941ebab86768b7e6a67f3
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spelling oai:doaj.org-article:d7cb546281f941ebab86768b7e6a67f32021-12-02T15:35:32ZCharacterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe10.1038/s41467-019-12392-22041-1723https://doaj.org/article/d7cb546281f941ebab86768b7e6a67f32019-10-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-12392-2https://doaj.org/toc/2041-1723In addition to serotonin neurons, the dorsal raphe nucleus (DR) also contains dopamine, glutamate, and GABA neurons. Here, the authors systematically compare the neurochemical identity, cell type specificity, anatomical distribution, and connectivity of DR cells targeted by commonly used Cre lines.Daniel F. Cardozo PintoHongbin YangIskra Pollak DorocicJohannes W. de JongVivian J. HanJames R. PeckYichen ZhuChristine LiuKevin T. BeierMarten P. SmidtStephan LammelNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Daniel F. Cardozo Pinto
Hongbin Yang
Iskra Pollak Dorocic
Johannes W. de Jong
Vivian J. Han
James R. Peck
Yichen Zhu
Christine Liu
Kevin T. Beier
Marten P. Smidt
Stephan Lammel
Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
description In addition to serotonin neurons, the dorsal raphe nucleus (DR) also contains dopamine, glutamate, and GABA neurons. Here, the authors systematically compare the neurochemical identity, cell type specificity, anatomical distribution, and connectivity of DR cells targeted by commonly used Cre lines.
format article
author Daniel F. Cardozo Pinto
Hongbin Yang
Iskra Pollak Dorocic
Johannes W. de Jong
Vivian J. Han
James R. Peck
Yichen Zhu
Christine Liu
Kevin T. Beier
Marten P. Smidt
Stephan Lammel
author_facet Daniel F. Cardozo Pinto
Hongbin Yang
Iskra Pollak Dorocic
Johannes W. de Jong
Vivian J. Han
James R. Peck
Yichen Zhu
Christine Liu
Kevin T. Beier
Marten P. Smidt
Stephan Lammel
author_sort Daniel F. Cardozo Pinto
title Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
title_short Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
title_full Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
title_fullStr Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
title_full_unstemmed Characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
title_sort characterization of transgenic mouse models targeting neuromodulatory systems reveals organizational principles of the dorsal raphe
publisher Nature Portfolio
publishDate 2019
url https://doaj.org/article/d7cb546281f941ebab86768b7e6a67f3
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