Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002

Background and Objective: One of the most important mutations, which occur in hepatitis B virus, is precore mutant. This mutation is associated with highly productive infection in anti-HBe+ chronic HBV carriers. These chronic HBV carriers are predisposed to developing active hepatitis. The aim of th...

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Autores principales:	MR Hassanjani Roshan, MJ Soleimani, A Asghar Zadeh Ahmadi
Formato:	article
Lenguaje:	EN FA
Publicado:	Babol University of Medical Sciences 2004
Materias:	prevalence precore mutant anti-hbe<sup>+</sup> chronic hbv infection Medicine R Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/d7d2b281f9914f33822c4796396a4fc9
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spelling	oai:doaj.org-article:d7d2b281f9914f33822c4796396a4fc92021-11-10T09:16:19ZPrevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 20021561-41072251-7170https://doaj.org/article/d7d2b281f9914f33822c4796396a4fc92004-10-01T00:00:00Zhttp://jbums.org/article-1-2670-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Background and Objective: One of the most important mutations, which occur in hepatitis B virus, is precore mutant. This mutation is associated with highly productive infection in anti-HBe+ chronic HBV carriers. These chronic HBV carriers are predisposed to developing active hepatitis. The aim of this study was to determine the prevalence of HBV DNA in chronic anti-HBe+ HBV carriers in Babol. Methods: This cross-sectional study was conducted on patients with anti-HBe+ chronic HBV carriers in Babol during 2002. In all cases, HBV DNA was assayed by PCR. Prevalence of HBV DNA is males, females and different age groups were compared with X² test. Findings: Of 257 cases of anti-HBe+ (Mean age±SD, 32.3±11.2 years), HBV DNA was positive in 222 (86.4%) cases. HBV DNA was positive in 136 (87.2%) of 156 males and 86 (85.15%) of 101 female cases (P=0.7). There was no significant difference in prevalence of HBV DNA between age groups (P=0.07). Conclusion: These research show that the high prevalence of HBV precore mutants in this region. Follow up of these individuals are necessary.MR Hassanjani RoshanMJ SoleimaniA Asghar Zadeh AhmadiBabol University of Medical Sciencesarticleprevalenceprecore mutantanti-hbe<sup>+</sup>chronic hbv infectionMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 6, Iss 4, Pp 49-53 (2004)
institution	DOAJ
collection	DOAJ
language	EN FA
topic	prevalence precore mutant anti-hbe<sup>+</sup> chronic hbv infection Medicine R Medicine (General) R5-920
spellingShingle	prevalence precore mutant anti-hbe<sup>+</sup> chronic hbv infection Medicine R Medicine (General) R5-920 MR Hassanjani Roshan MJ Soleimani A Asghar Zadeh Ahmadi Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
description	Background and Objective: One of the most important mutations, which occur in hepatitis B virus, is precore mutant. This mutation is associated with highly productive infection in anti-HBe+ chronic HBV carriers. These chronic HBV carriers are predisposed to developing active hepatitis. The aim of this study was to determine the prevalence of HBV DNA in chronic anti-HBe+ HBV carriers in Babol. Methods: This cross-sectional study was conducted on patients with anti-HBe+ chronic HBV carriers in Babol during 2002. In all cases, HBV DNA was assayed by PCR. Prevalence of HBV DNA is males, females and different age groups were compared with X² test. Findings: Of 257 cases of anti-HBe+ (Mean age±SD, 32.3±11.2 years), HBV DNA was positive in 222 (86.4%) cases. HBV DNA was positive in 136 (87.2%) of 156 males and 86 (85.15%) of 101 female cases (P=0.7). There was no significant difference in prevalence of HBV DNA between age groups (P=0.07). Conclusion: These research show that the high prevalence of HBV precore mutants in this region. Follow up of these individuals are necessary.
format	article
author	MR Hassanjani Roshan MJ Soleimani A Asghar Zadeh Ahmadi
author_facet	MR Hassanjani Roshan MJ Soleimani A Asghar Zadeh Ahmadi
author_sort	MR Hassanjani Roshan
title	Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
title_short	Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
title_full	Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
title_fullStr	Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
title_full_unstemmed	Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002
title_sort	prevalence of hbv dna in anti-hbe+ chronic hbv carriers in babol, 2002
publisher	Babol University of Medical Sciences
publishDate	2004
url	https://doaj.org/article/d7d2b281f9914f33822c4796396a4fc9
work_keys_str_mv	AT mrhassanjaniroshan prevalenceofhbvdnainantihbechronichbvcarriersinbabol2002 AT mjsoleimani prevalenceofhbvdnainantihbechronichbvcarriersinbabol2002 AT aasgharzadehahmadi prevalenceofhbvdnainantihbechronichbvcarriersinbabol2002
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Prevalence of HBV DNA in anti-HBe+ chronic HBV carriers in Babol, 2002

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