Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient

Thrombotic microangiopathy (TMA) is a rare disease that presents with haemolysis and organ damage. The kidney is one of the main affected organs, and TMA is associated with serious complications and increased mortality. In transplanted patients, TMA is even less common and has a variety of possible...

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Autores principales:	Carolina Ormonde, Sara Querido, Nuno Rombo, Rita Roque, Belarmino Clemente, André Weigert
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Surgery RD1-811
Acceso en línea:	https://doaj.org/article/d7d616f8441f4fe7b7863232154310c7
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spelling	oai:doaj.org-article:d7d616f8441f4fe7b7863232154310c72021-11-29T00:55:53ZPrimary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient2090-695110.1155/2021/9261371https://doaj.org/article/d7d616f8441f4fe7b7863232154310c72021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/9261371https://doaj.org/toc/2090-6951Thrombotic microangiopathy (TMA) is a rare disease that presents with haemolysis and organ damage. The kidney is one of the main affected organs, and TMA is associated with serious complications and increased mortality. In transplanted patients, TMA is even less common and has a variety of possible causes, including thrombotic thrombocytopenic purpura (TTP) and haemolytic-uremic syndrome (HUS), infections, drugs, autoimmune disease, tumours, and malignant hypertension. Transplant-related causes, such as antibody-mediated rejection, calcineurin inhibitors, and viral infections, need to be considered as well. The authors report a rare case of TMA in a kidney transplant recipient, whose investigation revealed malignant hypertension secondary to primary hyperaldosteronism.Carolina OrmondeSara QueridoNuno RomboRita RoqueBelarmino ClementeAndré WeigertHindawi LimitedarticleSurgeryRD1-811ENCase Reports in Transplantation, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Surgery RD1-811
spellingShingle	Surgery RD1-811 Carolina Ormonde Sara Querido Nuno Rombo Rita Roque Belarmino Clemente André Weigert Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
description	Thrombotic microangiopathy (TMA) is a rare disease that presents with haemolysis and organ damage. The kidney is one of the main affected organs, and TMA is associated with serious complications and increased mortality. In transplanted patients, TMA is even less common and has a variety of possible causes, including thrombotic thrombocytopenic purpura (TTP) and haemolytic-uremic syndrome (HUS), infections, drugs, autoimmune disease, tumours, and malignant hypertension. Transplant-related causes, such as antibody-mediated rejection, calcineurin inhibitors, and viral infections, need to be considered as well. The authors report a rare case of TMA in a kidney transplant recipient, whose investigation revealed malignant hypertension secondary to primary hyperaldosteronism.
format	article
author	Carolina Ormonde Sara Querido Nuno Rombo Rita Roque Belarmino Clemente André Weigert
author_facet	Carolina Ormonde Sara Querido Nuno Rombo Rita Roque Belarmino Clemente André Weigert
author_sort	Carolina Ormonde
title	Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
title_short	Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
title_full	Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
title_fullStr	Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
title_full_unstemmed	Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient
title_sort	primary hyperaldosteronism: a rare cause of malignant hypertension with thrombotic microangiopathy in a kidney transplant recipient
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/d7d616f8441f4fe7b7863232154310c7
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Primary Hyperaldosteronism: A Rare Cause of Malignant Hypertension with Thrombotic Microangiopathy in a Kidney Transplant Recipient

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